About this Research Topic

Background

Age-related diseases (ARDs) are a significant contributor to global morbidity and mortality, particularly in developed nations where the population is increasingly aged. As individuals grow older, the risk of developing a variety of chronic conditions, such as cardiovascular diseases, neurodegenerative disorders, and metabolic syndromes, increases dramatically. These diseases not only diminish the quality of life but also place a substantial burden on healthcare systems and economies.

The biological aging process is driven by complex molecular and cellular mechanisms, including genomic instability, telomere attrition, epigenetic alterations, and mitochondrial dysfunction. Recent advances in aging research have begun to unravel these processes, offering new insights into potential interventions that could delay or prevent the onset of age-related diseases. Interventions that target the underlying mechanisms of aging, rather than just the symptoms, hold promise for extending healthy lifespan and reducing the overall burden of ARDs.

The aim of the current Research Topic is to cover promising, recent, and novel research trends in the field of aging and age-related disease prevention. Areas to be covered in this Research Topic may include, but are not limited to:

•Epidemiological and economic analyses of age-related disease impact
•Reviews and meta-analyses on aging biomarkers and interventions
•Studies on the biological and molecular basis of interventions targeting aging
•Development and application of therapeutics that slow biological aging
•Predictions of the impact of aging interventions on population health and economics

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Clinical Trial
• Editorial
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Clinical Trial
• Editorial
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Technology and Code

Keywords: Age-related diseases, aging biomarkers, therapeutic interventions, aging mechanisms, epidemiology

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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