About this Research Topic
Reviews in Non-Neuronal Cells will publish high-quality scholarly review papers on key topics related to non-neuronal cells within the nervous system. This particular Research Topic will focus on “Roles and Mechanisms of Non-Neuronal Cells in Health and Disease”.
Non-neuronal cells, including resident immune cells, glial cells (astrocytes and cells of the oligodendrocytic lineage), neurovascular cells (endothelial cells, pericytes, perivascular macrophages, etc.), and other cells from the peripheral innate or adaptive immune systems, play crucial roles in maintaining and modulating the function and integrity of the nervous system. These cells are involved in neurovascular coupling, neuro-immune and neuro-glial communication, and the regulation of the neurovascular unit and neural barrier functions.
Non-neuronal cells significantly contribute to neural metabolism, inflammation, and immunity, impacting various physiological and pathological states across different stages of life and species. Their interactions with neurons and each other shape the neuroenvironment, influencing processes such as neurodevelopment, neuroprotection, and neurodegeneration.
This Research Topic aims to spotlight current advances in understanding the mechanisms and functions of non-neuronal cells in the nervous system. Areas of focus include but are not limited to neurovascular interactions, neuro-immune responses, glial cell functions, and the roles of these cells in neurological diseases and disorders. By elucidating the complex roles of non-neuronal cells, we hope to uncover new insights into their contributions to both healthy and diseased states.
Please note, only review articles will be accepted for this Research Topic. New articles will be added to this collection as they are published.
Keywords: Reviews, Non-neuronal cells, Neurovascular Coupling, Neuro-Immune Communication, Glial Cell Functions, Neurodevelopment and Neuroprotection, Neuroinflammation and Immunity
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.