Frontiers | Membrane Transporters and Channels as Targets for Drugs

Membrane Transporters and Channels as Targets for Drugs

48k
Total downloads
282k
Total views and downloads

Download PDF Download EPUB

Articles

ORIGINAL RESEARCH

Published on 04 Sep 2018

Relevance of Copper and Organic Cation Transporters in the Activity and Transport Mechanisms of an Anticancer Cyclometallated Gold(III) Compound in Comparison to Cisplatin

Sarah Spreckelmeyer
Margot van der Zee
Benoît Bertrand
Ewen Bodio
Stefan Stürup
Angela Casini

doi 10.3389/fchem.2018.00377

3,877 views
21 citations

ORIGINAL RESEARCH

Published on 24 Aug 2018

Activation of the Calcium-Sensing Receptor Corrects the Impaired Mitochondrial Energy Status Observed in Renal Polycystin-1 Knockdown Cells Modeling Autosomal Dominant Polycystic Kidney Disease

Annarita Di Mise
Marianna Ranieri
Mariangela Centrone
Maria Venneri
Grazia Tamma
Daniela Valenti
Giovanna Valenti

doi 10.3389/fmolb.2018.00077

4,066 views
19 citations

ORIGINAL RESEARCH

Published on 24 Aug 2018

In silico Description of LAT1 Transport Mechanism at an Atomistic Level

Luca Palazzolo
Chiara Parravicini
Tommaso Laurenzi
Uliano Guerrini
Cesare Indiveri
Elisabetta Gianazza
Ivano Eberini

doi 10.3389/fchem.2018.00350

5,192 views
13 citations

ORIGINAL RESEARCH

Published on 15 Aug 2018

ENaC in Cholinergic Brush Cells

Chrissy Kandel
Patricia Schmidt
Alexander Perniss
Maryam Keshavarz
Paul Scholz
Sabrina Osterloh
Mike Althaus
Wolfgang Kummer
Klaus Deckmann

doi 10.3389/fcell.2018.00089

20,088 views
7 citations

REVIEW

Published on 14 Aug 2018

TRP Channels as Potential Targets for Sex-Related Differences in Migraine Pain

Maite Artero-Morales
Sara González-Rodríguez
Antonio Ferrer-Montiel

doi 10.3389/fmolb.2018.00073

27,820 views
42 citations

ORIGINAL RESEARCH

Published on 14 Aug 2018

Extracellular ATP Regulates CD73 and ABCC6 Expression in HepG2 Cells

Fabio Martinelli
Flavia Cuviello
Maria C. Pace
Maria F. Armentano
Rocchina Miglionico
Angela Ostuni
Faustino Bisaccia

doi 10.3389/fmolb.2018.00075

3,353 views
20 citations

ORIGINAL RESEARCH

Published on 24 Jul 2018

Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

Rachel-Ann A. Garibsingh
Nicholas J. Otte
Elias Ndaru
Claire Colas
Christof Grewer
Jeff Holst
Avner Schlessinger

doi 10.3389/fchem.2018.00279

4,564 views
22 citations

REVIEW

Published on 10 Jul 2018

Aquaglyceroporins: Drug Targets for Metabolic Diseases?

Giuseppe Calamita
Jason Perret
Christine Delporte

doi 10.3389/fphys.2018.00851

4,924 views
53 citations

ORIGINAL RESEARCH

Published on 04 Jul 2018

The Sodium Sialic Acid Symporter From Staphylococcus aureus Has Altered Substrate Specificity

Rachel A. North
Weixiao Y. Wahlgren
Daniela M. Remus
Mariafrancesca Scalise
Sarah A. Kessans
Elin Dunevall
Elin Claesson
Tatiana P. Soares da Costa
Matthew A. Perugini
4 more
Renwick C. J. Dobson

doi 10.3389/fchem.2018.00233

4,397 views
28 citations

REVIEW

Published on 28 Jun 2018

P2RX7 Purinoceptor as a Therapeutic Target—The Second Coming?

Chris N. J. Young
Dariusz C. Górecki

doi 10.3389/fchem.2018.00248

9,993 views
73 citations

REVIEW

Published on 22 Jun 2018

The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health

Mariafrancesca Scalise
Michele Galluccio
Lara Console
Lorena Pochini
Cesare Indiveri

doi 10.3389/fchem.2018.00243

42,863 views
225 citations

MINI REVIEW

Published on 21 Jun 2018

The Emerging Role of microRNAs in Aquaporin Regulation

André Gomes
Inês V. da Silva
Cecília M. P. Rodrigues
Rui E. Castro
Graça Soveral

doi 10.3389/fchem.2018.00238

4,774 views
34 citations

Share on

Frontiers in Chemistry

Cellular BiochemistryOffline
Chemical Biology

Participating Journals

Frontiers in Cell and Developmental Biology
- Cellular Biochemistry
- 4.6 impact factor
- 9.7 citescore
Frontiers in Molecular Biosciences
- Cellular Biochemistry
- 3.9 impact factor
- 7.2 citescore
Frontiers in Physiology
- Membrane Physiology and Membrane Biophysics
- 3.2 impact factor
- 6.5 citescore

Impact

282kTopic views
226kArticle views
48kArticle downloads

View impact

Submit your idea

Articles

Relevance of Copper and Organic Cation Transporters in the Activity and Transport Mechanisms of an Anticancer Cyclometallated Gold(III) Compound in Comparison to Cisplatin

Activation of the Calcium-Sensing Receptor Corrects the Impaired Mitochondrial Energy Status Observed in Renal Polycystin-1 Knockdown Cells Modeling Autosomal Dominant Polycystic Kidney Disease

In silico Description of LAT1 Transport Mechanism at an Atomistic Level

ENaC in Cholinergic Brush Cells

TRP Channels as Potential Targets for Sex-Related Differences in Migraine Pain

Extracellular ATP Regulates CD73 and ABCC6 Expression in HepG2 Cells

Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

Aquaglyceroporins: Drug Targets for Metabolic Diseases?

The Sodium Sialic Acid Symporter From Staphylococcus aureus Has Altered Substrate Specificity

P2RX7 Purinoceptor as a Therapeutic Target—The Second Coming?

The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health

The Emerging Role of microRNAs in Aquaporin Regulation

Frontiers in Chemistry

Participating Journals

Impact