The global incidence of immune-related digestive system cancers is rising, significantly impacting patients' quality of life and health. Additionally, the progression and metastasis of digestive system tumors pose severe challenges due to the complex tumor microenvironment and the immune response mechanisms involved. These diseases often involve intricate pathophysiological mechanisms, including abnormal activation of the immune system and persistent inflammation. In recent years, advances in molecular biology and immunology have enhanced our understanding of these mechanisms, providing a scientific basis for developing new therapeutic strategies. While traditional treatment methods such as chemotherapy and radiotherapy can control tumor progression, their side effects and long-term efficacy remain controversial. Emerging immunotherapies and targeted therapies offer new hope, particularly for patients with metastatic digestive system cancers. However, developing precise treatment plans tailored to individual differences remains a significant challenge. The integration of multidisciplinary collaboration and personalized treatment strategies shows considerable promise in improving treatment outcomes and prognosis, becoming a crucial focus in current research and practice.
The primary goals of this research topic are to summarize the latest treatment methods and techniques for immune-related digestive system cancers, analyze the clinical outcomes and prognoses of various treatment approaches, explore the molecular mechanisms and biomarkers of immune factors related to the progression of these cancers, and share successful case studies and lessons learned to enhance clinical treatment standards.
This research topic will encompass a broad range of themes, with a particular emphasis on the following types of articles:
Review Articles:
• Epidemiology and Pathophysiology of Immune-Related Digestive System Cancer progression and metastasis: Investigate the roles and influencing factors of immune factors in digestive system cancer.
• Latest Treatment Techniques and Methods: Include immunotherapy, targeted therapy, and discuss their indications and limitations.
• Molecular Mechanisms and Biomarkers: Study the molecular mechanisms associated with immune-related digestive system cancer progression and metastasis, explore potential biomarkers, and provide insights for precision medicine.
Clinical Experience:
• Multidisciplinary Collaborative Treatment Models: Share collaborative experiences and successful cases from multidisciplinary teams in treating immune-related digestive system cancer progression and metastasis.
• Personalized Treatment Strategies: Develop and evaluate individualized comprehensive treatment plans based on specific patient conditions, assessing their efficacy and safety.
Case Reports:
• Typical Case Analysis: Present representative cases of immune-related digestive system cancer progression and metastasis for detailed analysis, highlighting key points and lessons learned during the treatment process.
• Rare Case Reports: Document rare cases of immune-related digestive system cancer progression and metastasis, discussing their uniqueness and the challenges encountered in treatment.
Keywords:
digestive cancer, progression, metastasis, immunology, treatment strategies, clinical outcomes
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
The global incidence of immune-related digestive system cancers is rising, significantly impacting patients' quality of life and health. Additionally, the progression and metastasis of digestive system tumors pose severe challenges due to the complex tumor microenvironment and the immune response mechanisms involved. These diseases often involve intricate pathophysiological mechanisms, including abnormal activation of the immune system and persistent inflammation. In recent years, advances in molecular biology and immunology have enhanced our understanding of these mechanisms, providing a scientific basis for developing new therapeutic strategies. While traditional treatment methods such as chemotherapy and radiotherapy can control tumor progression, their side effects and long-term efficacy remain controversial. Emerging immunotherapies and targeted therapies offer new hope, particularly for patients with metastatic digestive system cancers. However, developing precise treatment plans tailored to individual differences remains a significant challenge. The integration of multidisciplinary collaboration and personalized treatment strategies shows considerable promise in improving treatment outcomes and prognosis, becoming a crucial focus in current research and practice.
The primary goals of this research topic are to summarize the latest treatment methods and techniques for immune-related digestive system cancers, analyze the clinical outcomes and prognoses of various treatment approaches, explore the molecular mechanisms and biomarkers of immune factors related to the progression of these cancers, and share successful case studies and lessons learned to enhance clinical treatment standards.
This research topic will encompass a broad range of themes, with a particular emphasis on the following types of articles:
Review Articles:
• Epidemiology and Pathophysiology of Immune-Related Digestive System Cancer progression and metastasis: Investigate the roles and influencing factors of immune factors in digestive system cancer.
• Latest Treatment Techniques and Methods: Include immunotherapy, targeted therapy, and discuss their indications and limitations.
• Molecular Mechanisms and Biomarkers: Study the molecular mechanisms associated with immune-related digestive system cancer progression and metastasis, explore potential biomarkers, and provide insights for precision medicine.
Clinical Experience:
• Multidisciplinary Collaborative Treatment Models: Share collaborative experiences and successful cases from multidisciplinary teams in treating immune-related digestive system cancer progression and metastasis.
• Personalized Treatment Strategies: Develop and evaluate individualized comprehensive treatment plans based on specific patient conditions, assessing their efficacy and safety.
Case Reports:
• Typical Case Analysis: Present representative cases of immune-related digestive system cancer progression and metastasis for detailed analysis, highlighting key points and lessons learned during the treatment process.
• Rare Case Reports: Document rare cases of immune-related digestive system cancer progression and metastasis, discussing their uniqueness and the challenges encountered in treatment.
Keywords:
digestive cancer, progression, metastasis, immunology, treatment strategies, clinical outcomes
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.