About this Research Topic
Background:
Infectious diseases represent a significant risk to human health, causing approximately more than half of deaths worldwide. However, the human body has mechanisms that are capable of recognizing and identifying infections caused by pathogens and defending the organism, through the early reactions of innate immunity and the late reactions of adaptive immunity. These mechanisms involve essential components of the innate and adaptive immune systems, including molecular and soluble immune mediators, and several cell types, such as neutrophils, monocytes, macrophages, eosinophils, mast cells, and dendritic cells. These cells detect pathogen-associated molecular patterns (PAMPs), through recognition receptors, to produce inflammatory mediators. These components work together to amplify the inflammatory response and thus activate the adaptive immune response through antigen presentation, generating two types of immunity, humoral and cellular, to combat infections caused by bacteria, viruses, fungi, and parasites, to eliminate them and eradicate the infection from the host. However, on some occasions, the immune system cannot resolve the various diseases caused by pathogens. This is why it is necessary to apply some type of therapy, whether pharmacological, immunological, etc., to resolve the disease.
Goal:
Currently, diseases caused by pathogenic agents are of great interest and importance in the biomedical field, due to the impact that they have on the health of the human population. Therefore, the main objective of this special issue is to show recent advances in aspects at the molecular level, which are involved in the immune responses that the host mounts against different pathogenic agents, such as viruses, bacteria, parasites, and fungi. Likewise, this special issue aims to provide current information on the pathological and clinical aspects of infections and diseases caused by these pathogens.
Scope:
Based on the main objective of this special issue, different authors are invited to participate in publishing manuscripts on the current molecular, immunological, pathological, and clinical aspects of pathogenic infections.
Manuscripts on bacteria, viruses, parasites, and fungi are welcome. As well as manuscripts on infections and diseases caused by pathogens, pathological, molecular, and immunological mechanisms. Furthermore, manuscripts that link molecular mechanisms to clinical pathology aspects, inflammation, novel treatments, pharmacotherapy, and immunotherapy are invited.
Based on the type and design of the study, manuscripts on in vivo and in vitro studies of any type, reviews, systematic reviews, original research, short communications, Brief Research Reports, Data Reports, and Case Reports are invited.
Infectious diseases represent a significant risk to human health, causing approximately more than half of deaths worldwide. However, the human body has mechanisms that are capable of recognizing and identifying infections caused by pathogens and defending the organism, through the early reactions of innate immunity and the late reactions of adaptive immunity. These mechanisms involve essential components of the innate and adaptive immune systems, including molecular and soluble immune mediators, and several cell types, such as neutrophils, monocytes, macrophages, eosinophils, mast cells, and dendritic cells. These cells detect pathogen-associated molecular patterns (PAMPs), through recognition receptors, to produce inflammatory mediators. These components work together to amplify the inflammatory response and thus activate the adaptive immune response through antigen presentation, generating two types of immunity, humoral and cellular, to combat infections caused by bacteria, viruses, fungi, and parasites, to eliminate them and eradicate the infection from the host. However, on some occasions, the immune system cannot resolve the various diseases caused by pathogens. This is why it is necessary to apply some type of therapy, whether pharmacological, immunological, etc., to resolve the disease.
Goal:
Currently, diseases caused by pathogenic agents are of great interest and importance in the biomedical field, due to the impact that they have on the health of the human population. Therefore, the main objective of this special issue is to show recent advances in aspects at the molecular level, which are involved in the immune responses that the host mounts against different pathogenic agents, such as viruses, bacteria, parasites, and fungi. Likewise, this special issue aims to provide current information on the pathological and clinical aspects of infections and diseases caused by these pathogens.
Scope:
Based on the main objective of this special issue, different authors are invited to participate in publishing manuscripts on the current molecular, immunological, pathological, and clinical aspects of pathogenic infections.
Manuscripts on bacteria, viruses, parasites, and fungi are welcome. As well as manuscripts on infections and diseases caused by pathogens, pathological, molecular, and immunological mechanisms. Furthermore, manuscripts that link molecular mechanisms to clinical pathology aspects, inflammation, novel treatments, pharmacotherapy, and immunotherapy are invited.
Based on the type and design of the study, manuscripts on in vivo and in vitro studies of any type, reviews, systematic reviews, original research, short communications, Brief Research Reports, Data Reports, and Case Reports are invited.
Keywords: Bacteria, Virus, Parasites, Fungi, Infections and diseases caused by Pathogens, Pathological mechanisms, Molecular mechanisms, Immunological mechanisms, Clinical-pathology Inflammation, Novel treatments, Pharmacotherapy, Immunotherapy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
