Frontiers | Harnessing Big Data for Precision Medicine: Revolutionizing Diagnosis and Treatment Strategies

Harnessing Big Data for Precision Medicine: Revolutionizing Diagnosis and Treatment Strategies

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ORIGINAL RESEARCH

Published on 14 Jan 2025

Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activating the Nrf2/HO-1 pathway

Jiaochen Luan
Mengchi Yu
Qi Gu
Xuan Zhou
Yunqiang Shao
Tong Chen
Jiayi Zhang
Zheng Zhu
Ninghong Song
Jie Yang

doi 10.3389/fimmu.2024.1532021

ORIGINAL RESEARCH

Accepted on 13 Jan 2025

Interpretable Machine Learning and Radiomics in Hip MRI Diagnostics: Comparing ONFH and OA Predictions to Experts

Tariq Alkhatatbeh
Ahmad Alkhatatbeh
Qin Guo
Jiechen Chen
Jidong Song
Xingru Qini
Wang Wei

doi 10.3389/fimmu.2025.1532248

ORIGINAL RESEARCH

Accepted on 10 Jan 2025

Development and validation of a machine learning model to predict the risk of lymph node metastasis in early-stage supraglottic laryngeal cancer

Hongyu Wang
Zhiqiang He
Jiayang Xu
Ting Chen
Jingtian Huang
Lihong Chen
Xin Yue

doi 10.3389/fonc.2025.1525414

167 views

ORIGINAL RESEARCH

Published on 10 Jan 2025

Developing and validating a machine learning model to predict multidrug-resistant Klebsiella pneumoniae-related septic shock

Shengnan Pan
Ting Shi
Jinling Ji
Kai Wang
Kun Jiang
Yabin Yu
Chang Li

doi 10.3389/fimmu.2024.1539465

330 views

ORIGINAL RESEARCH

Published on 10 Jan 2025

Glycosylation profiling of triple-negative breast cancer: clinical and immune correlations and identification of LMAN1L as a biomarker and therapeutic target

Qianru Yu
Hanyi Zhong
Xinhao Zhu
Chang Liu
Xin Zhang
Jiao Wang
Zongyao Li
Songchang Shi
Haoran Zhao
1 more
Qian Zhao

doi 10.3389/fimmu.2024.1521930

134 views

MINI REVIEW

Published on 10 Jan 2025

Tuberculous meningitis diagnosis and treatment: classic approaches and high-throughput pathways

Fangbo Lin

doi 10.3389/fimmu.2024.1543009

136 views

ORIGINAL RESEARCH

Published on 09 Jan 2025

DET induces apoptosis and suppresses tumor invasion in glioma cells via PI3K/AKT pathway

Rui Zhao
Mengran Wang
Zeyu Wu
Panpan Zhao
Huiling Dong
Yue Su
Chenghui Zhao
Min Qi
Shizhang Ling
Xiaochun Jiang

doi 10.3389/fonc.2024.1528454

188 views

ORIGINAL RESEARCH

Published on 07 Jan 2025

Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer

Zhiheng Lin
Fengxin Wang
Renwu Yin
Shengnan Li
Yuquan Bai
Baofang Zhang
Chenlin Sui
Hengjie Cao
Dune Su
1 more
Honghong Wang

doi 10.3389/fimmu.2024.1522655

204 views

ORIGINAL RESEARCH

Accepted on 03 Jan 2025

Identification of WDR74 and TNFRSF12A as Biomarkers for Early Osteoarthritis Using Machine Learning and Immunohistochemistry

Yiwei Chen
Jiali Lin
Detong Shi
Yu Miao
Feng Xue
Kexin Liu
Xiaotao Wang
Changqing Zhang

doi 10.3389/fimmu.2025.1517646

MINI REVIEW

Accepted on 02 Jan 2025

Overcoming immune evasion with innovative multi-target approaches for glioblastoma

Hai Su
Yin Peng
Yilong Wu
Xiaoli Zeng

doi 10.3389/fimmu.2025.1541467

ORIGINAL RESEARCH

Accepted on 30 Dec 2024

The Role of Isoniazid Dosage and NAT2 Gene Polymorphism in the Treatment of Tuberculous Meningitis

Yi Jian
Yuhang Bao
Fashuang Yang
Mei Zhu

doi 10.3389/fimmu.2024.1535447

ORIGINAL RESEARCH

Accepted on 30 Dec 2024

Pan-cancer analysis of the transcriptional expression of histone acetylation enzymes in solid tumors defines a new classification scheme for gliomas

Junhao Zhang
Lingbo Li
Aiwei Tang
Chucheng Wang
Yupeng Wang
Yongqi Hu
Guangting He
Wangjun Liao
Rui Zhou

doi 10.3389/fimmu.2024.1523034

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Frontiers in Immunology

Cancer Immunity and Immunotherapy
Inflammation

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Frontiers in Oncology
- Cancer Immunity and Immunotherapy
- 3.5 impact factor
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Articles

Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activating the Nrf2/HO-1 pathway

Interpretable Machine Learning and Radiomics in Hip MRI Diagnostics: Comparing ONFH and OA Predictions to Experts

Development and validation of a machine learning model to predict the risk of lymph node metastasis in early-stage supraglottic laryngeal cancer

Developing and validating a machine learning model to predict multidrug-resistant Klebsiella pneumoniae-related septic shock

Glycosylation profiling of triple-negative breast cancer: clinical and immune correlations and identification of LMAN1L as a biomarker and therapeutic target

Tuberculous meningitis diagnosis and treatment: classic approaches and high-throughput pathways

DET induces apoptosis and suppresses tumor invasion in glioma cells via PI3K/AKT pathway

Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer

Identification of WDR74 and TNFRSF12A as Biomarkers for Early Osteoarthritis Using Machine Learning and Immunohistochemistry

Overcoming immune evasion with innovative multi-target approaches for glioblastoma

The Role of Isoniazid Dosage and NAT2 Gene Polymorphism in the Treatment of Tuberculous Meningitis

Pan-cancer analysis of the transcriptional expression of histone acetylation enzymes in solid tumors defines a new classification scheme for gliomas

Frontiers in Immunology

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