About this Research Topic

Background

Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cell (MSC) found in the dental pulp, the innermost part of the tooth. Since their discovery, DPSCs have attracted significant attention due to their high proliferation rate, remarkable differentiation potential, and ease of accessibility. DPSCs have shown promise in various regenerative medicine applications, including dental tissue regeneration, bone repair, and even neurological and cardiac therapies. The unique properties of DPSCs, combined with the ease of obtaining them from extracted teeth, make them an attractive cell source for tissue engineering and regenerative medicine.

This Research Topic aims to consolidate recent advancements in the field of DPSCs, focusing on their applications, signaling pathways, and molecular mechanisms. The goal is to provide a comprehensive overview of the current state of DPSCs research and discuss future directions and potential therapeutic applications.

Areas of interest may cover but are not limited to:

1. Molecular mechanisms underpinning DPSC functionality

2. Signaling pathways in DPSC differentiation, proliferation, and self-renewal

3. Role of external factors in DPSC fate e.g., growth factors, cytokines, and extracellular matrix components

4. Applications of DPSCs in tissue regeneration, including dental tissue regeneration, bone tissue engineering, neuroregeneration, cardiac regeneration, etc.

5. Advances in DPSC isolation, and characterization techniques

6. Scaffolds and delivery systems for enhancing DPSC-based tissue engineering.

7. Models to study DPSC and their applications.

The editors welcome different article types including Original Research, Reviews and Mini-Reviews, Methods, Brief Research Reports, and Perspectives. A full list of accepted article types, including descriptions, can be found at this link.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Data Report
• Editorial
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Data Report
• Editorial
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Technology and Code

Keywords: dental pulp stem cells, mesenchymal stem cells, tissue regeneration, scaffolds, differentiation, proliferation, self-renewal

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