Stem cell regeneration is crucial for tissue repair, and it is a field that thrives on collaboration. Dynamic changes in stem cell niches support stem cells, but abnormal factors can disrupt their normal division and differentiation. For instance, mechanical forces and inflammation during disease progression can adversely affect stem cells. Cell-to-cell communication, such as between stem cells and immune cells, also plays a significant role in stem cell regeneration. The mechanisms that immune cells regulate stem cell behaviour and function remain unknown. Therefore, investigating the tissue microenvironment, understanding how various factors influence stem cells, and identifying key genes and pathways are imperative. We invite you to join us in this important work.
In recent years, stem cell regeneration has gained importance for tissue repair, and while several challenges require attention, there is also great potential. With aging, stem cells gradually deplete and lose their differentiation capacity, leading to conditions like osteoporosis. However, understanding the mechanisms of stem cell exhaustion and finding ways to preserve their function could lead to effective treatments. Techniques such as CRISPR-Cas9 and genetic engineering offer promising avenues for directing stem cell differentiation. Lastly, three-dimensional cultivation methods offer a superior way to study the tissue microenvironment, opening up new possibilities for research and discovery.
We aim to publish high-quality research on how the tissue microenvironment regulates stem cell regeneration. The journal will showcase significant advancements relevant to experts in each field.
• Tissue microenvironment
• Stem cell differentiation
• Tissue regeneration
• Biomaterials for stem cell differentiation
Keywords:
Tissue microenvironment; Stem cell differentiation; TiBiomaterials for stem cell differentiation
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Stem cell regeneration is crucial for tissue repair, and it is a field that thrives on collaboration. Dynamic changes in stem cell niches support stem cells, but abnormal factors can disrupt their normal division and differentiation. For instance, mechanical forces and inflammation during disease progression can adversely affect stem cells. Cell-to-cell communication, such as between stem cells and immune cells, also plays a significant role in stem cell regeneration. The mechanisms that immune cells regulate stem cell behaviour and function remain unknown. Therefore, investigating the tissue microenvironment, understanding how various factors influence stem cells, and identifying key genes and pathways are imperative. We invite you to join us in this important work.
In recent years, stem cell regeneration has gained importance for tissue repair, and while several challenges require attention, there is also great potential. With aging, stem cells gradually deplete and lose their differentiation capacity, leading to conditions like osteoporosis. However, understanding the mechanisms of stem cell exhaustion and finding ways to preserve their function could lead to effective treatments. Techniques such as CRISPR-Cas9 and genetic engineering offer promising avenues for directing stem cell differentiation. Lastly, three-dimensional cultivation methods offer a superior way to study the tissue microenvironment, opening up new possibilities for research and discovery.
We aim to publish high-quality research on how the tissue microenvironment regulates stem cell regeneration. The journal will showcase significant advancements relevant to experts in each field.
• Tissue microenvironment
• Stem cell differentiation
• Tissue regeneration
• Biomaterials for stem cell differentiation
Keywords:
Tissue microenvironment; Stem cell differentiation; TiBiomaterials for stem cell differentiation
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.