About this Research Topic
Cell metabolism is an essential process for cells to maintain their life activities. Impaired cellular metabolism triggers defects in several important molecules in the body, leading to the development of diseases, such as Wilson's Disease, which is caused by the dysfunction of cellular copper metabolism. Cellular metabolism has also now been shown to play an important role in the development of malignant tumors, e.g., lipid metabolism and amino acid metabolism, which can influence the survival of tumor cells by affecting the mitochondrial function of cells. However, the role of cellular metabolism on tumor cell proliferation, metastasis, and drug resistance still needs to be further explored.
This Research Topic aims to bring together novel content on cell metabolism about tumorigenesis, progression, drug resistance, and prognostic assessment, as well as articles on the identification of biomarkers using metabolomics approaches. We welcome content on cellular metabolism studies using cellular experiments, animal experiments, databases, and clinical cohort analyses. Cellular metabolism includes ferroptosis due to abnormal phospholipid metabolism, cuproptosis due to abnormal copper metabolism, and more. The pooling of this content can help discover new therapeutic targets for tumor suppression from a cellular metabolism perspective or a combination of drug approaches to reverse tumor resistance.
Thus, we aim to publish articles related to cell metabolism studies on cancers. Review and original research are welcome, including but not limited to the following contents:
• Clinical metabolomics in the context of cancers.
• The effect of cell metabolism on drug resistance of cancers.
• The relationship between gene mutation and cell metabolism.
• The prognostic assessment of patients with cancers by the metabolism-related biomarker.
This Research Topic aims to bring together novel content on cell metabolism about tumorigenesis, progression, drug resistance, and prognostic assessment, as well as articles on the identification of biomarkers using metabolomics approaches. We welcome content on cellular metabolism studies using cellular experiments, animal experiments, databases, and clinical cohort analyses. Cellular metabolism includes ferroptosis due to abnormal phospholipid metabolism, cuproptosis due to abnormal copper metabolism, and more. The pooling of this content can help discover new therapeutic targets for tumor suppression from a cellular metabolism perspective or a combination of drug approaches to reverse tumor resistance.
Thus, we aim to publish articles related to cell metabolism studies on cancers. Review and original research are welcome, including but not limited to the following contents:
• Clinical metabolomics in the context of cancers.
• The effect of cell metabolism on drug resistance of cancers.
• The relationship between gene mutation and cell metabolism.
• The prognostic assessment of patients with cancers by the metabolism-related biomarker.
Keywords: cellular metabolism, cancer, phospholipid metabolism, amino acid metabolism, drug resistance
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
