About this Research Topic
The interplay between cancer immunology, gene editing, and epigenetics presents a promising frontier for precision medicine. Exhaustion, and tumor infiltration, offers new avenues for potential therapeutic interventions in multiple disease settings. By elucidating the molecular mechanisms underlying immune responses, genetic alterations, and epigenetic changes in cancer, this special Research Topic collection seeks to drive forward the development of tailored and effective therapies. The main areas of focus for papers submitted to the collection are Integration of Cancer Immunology and Gene Editing, Epigenetic Regulation in Cancer Immunotherapy, Synergistic Effects of Combined Approaches and Clinical Implications and Future Directions. This collection will aim to acquire publications focused on but not limited to the following areas:
Exploring how gene editing technologies like CRISPR/Cas9 can enhance cancer immunotherapy by modifying immune cells to target tumors more effectively.
Investigating the role of gene editing in developing personalized and precise cancer treatments through engineered T-cells and immune cell modifications.
Understanding how epigenetic mechanisms influence the interactions between tumor cells and the immune system, impacting immune responses and tumor progression.
Examining the potential of epigenetic targeting agents to modulate immune responses and enhance the efficacy of immunotherapies in cancer treatment.
Highlighting the synergies between cancer immunology, gene editing, and epigenetics in developing novel therapeutic strategies for precision medicine in oncology.
Investigating how the interplay of these fields can lead to more effective and durable treatments by targeting specific genetic and epigenetic alterations in cancer cells.
Discussing the translational potential of integrating gene editing and epigenetic modulation into cancer immunotherapy for improved patient outcomes and reduced treatment resistance.
Through a comprehensive exploration of these interconnected fields, this special issue aims to shed light on novel approaches that hold the potential to transform the landscape of cancer treatment towards more precise and personalized interventions.
The collection will accept a range of article types focused on these areas of research including original research manuscripts, mini reviews and reviews. The collection editors declare that they have no conflicts of interest to declare in relation to the editorship of this Research Topic Collection.
Exploring how gene editing technologies like CRISPR/Cas9 can enhance cancer immunotherapy by modifying immune cells to target tumors more effectively.
Investigating the role of gene editing in developing personalized and precise cancer treatments through engineered T-cells and immune cell modifications.
Understanding how epigenetic mechanisms influence the interactions between tumor cells and the immune system, impacting immune responses and tumor progression.
Examining the potential of epigenetic targeting agents to modulate immune responses and enhance the efficacy of immunotherapies in cancer treatment.
Highlighting the synergies between cancer immunology, gene editing, and epigenetics in developing novel therapeutic strategies for precision medicine in oncology.
Investigating how the interplay of these fields can lead to more effective and durable treatments by targeting specific genetic and epigenetic alterations in cancer cells.
Discussing the translational potential of integrating gene editing and epigenetic modulation into cancer immunotherapy for improved patient outcomes and reduced treatment resistance.
Through a comprehensive exploration of these interconnected fields, this special issue aims to shed light on novel approaches that hold the potential to transform the landscape of cancer treatment towards more precise and personalized interventions.
The collection will accept a range of article types focused on these areas of research including original research manuscripts, mini reviews and reviews. The collection editors declare that they have no conflicts of interest to declare in relation to the editorship of this Research Topic Collection.
Keywords: epigenetics, cancer, immunity, cas9, gene editing
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
