About this Research Topic
Nano-therapeutics represent a transformative advancement in precision cancer medicine, offering the promise of more effective and targeted treatment options. By harnessing the unique properties of nanoparticles, such as their small size, large surface area, and the ability to be engineered for specific functions, researchers are pioneering novel approaches to cancer therapy. These nanomaterials can be designed to deliver therapeutic agents directly to tumor cells, thereby minimizing off-target effects and reducing systemic toxicity.
This precision is achieved through surface modifications that enable nanoparticles to bind selectively to cancer cell markers or through the use of stimuli-responsive systems that activate drug release only in the tumor microenvironment. Furthermore, nano-therapeutics can be employed to overcome challenges such as drug resistance and poor bioavailability of conventional therapies. For instance, nanoparticles can encapsulate hydrophobic drugs, enhancing their solubility and stability while facilitating sustained release. Additionally, the integration of imaging capabilities into nanoparticles allows for real-time monitoring of treatment efficacy and tumor progression, thus aiding in personalized treatment adjustments.
Nano-therapeutics play a pivotal role in the evolution of precision cancer medicine, providing tailored and effective solutions that align with the unique molecular profiles of individual tumors. Therefore, this Research Topic focuses on role of Nano-Therapeutics in Cancer. We welcome Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data notes, and technical notes, but are not limited to the following:
• Studies related to drug-delivery methods based on the genetic and molecular profile of individual tumors.
• Explore how nano-therapeutics can be used to circumvent mechanisms of drug resistance in cancer cells, including multi-drug resistance (MDR) pathways.
• Study the pharmacokinetics (absorption, distribution, metabolism, excretion) and pharmacodynamics (effects and mechanisms) of therapeutics to optimize dosing and effectiveness.
• Research on designing nanoparticles that specifically target tumor cells based on unique biomarkers or surface receptors.
This precision is achieved through surface modifications that enable nanoparticles to bind selectively to cancer cell markers or through the use of stimuli-responsive systems that activate drug release only in the tumor microenvironment. Furthermore, nano-therapeutics can be employed to overcome challenges such as drug resistance and poor bioavailability of conventional therapies. For instance, nanoparticles can encapsulate hydrophobic drugs, enhancing their solubility and stability while facilitating sustained release. Additionally, the integration of imaging capabilities into nanoparticles allows for real-time monitoring of treatment efficacy and tumor progression, thus aiding in personalized treatment adjustments.
Nano-therapeutics play a pivotal role in the evolution of precision cancer medicine, providing tailored and effective solutions that align with the unique molecular profiles of individual tumors. Therefore, this Research Topic focuses on role of Nano-Therapeutics in Cancer. We welcome Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data notes, and technical notes, but are not limited to the following:
• Studies related to drug-delivery methods based on the genetic and molecular profile of individual tumors.
• Explore how nano-therapeutics can be used to circumvent mechanisms of drug resistance in cancer cells, including multi-drug resistance (MDR) pathways.
• Study the pharmacokinetics (absorption, distribution, metabolism, excretion) and pharmacodynamics (effects and mechanisms) of therapeutics to optimize dosing and effectiveness.
• Research on designing nanoparticles that specifically target tumor cells based on unique biomarkers or surface receptors.
Keywords: Nanoparticle, Nanomedicine, Nanocarrier, Nanotechnology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
