New Concepts in Revascularization Strategies and Antithrombotic Therapies in Patients With Non-ST Elevated Acute Coronary Syndromes

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About this Research Topic

Submission deadlines

  1. Manuscript Submission Deadline 28 March 2025

  2. This Research Topic is still accepting articles.

Background

Non-ST elevation myocardial infarction (NSTEMI) represents a significant clinical entity within the spectrum of acute coronary syndromes (ACS). Frequently characterized by older patients and more complex anatomical and clinical scenarios than ST elevation MI (STEMI), NSTEMI poses unique challenges in diagnosis and treatment, necessitating a nuanced approach to management. Optimizing revascularization strategies and antithrombotic therapies is crucial for improving patient outcomes and reducing the risk of recurrent cardiovascular events.

This research topic seeks to consolidate recent advancements and emerging concepts in the management of NSTEMI, aiming to drive forward the understanding and treatment of this prevalent condition.

Themes and Topics of Interest:

1. Innovations in Revascularization Strategies:
o Comparative efficacy of early versus delayed revascularization approaches in NSTEMI.
o Advances in percutaneous coronary intervention (PCI) techniques specific to NSTEMI patients.
o Role of coronary artery bypass grafting (CABG) in the management of complex NSTEMI cases.
o Emerging technologies and devices in coronary revascularization.

2. Antithrombotic Therapies:
o Development and clinical implementation of novel antiplatelet agents.
o The role of dual vs. triple antithrombotic therapy in reducing thrombotic complications.
o Tailoring antithrombotic regimens based on patient-specific risk profiles and comorbidities.
o Long-term outcomes of different antithrombotic strategies in NSTEMI management.

3. Risk Stratification and Diagnostic Tools:
o Advances in biomarkers for early and accurate diagnosis of NSTEMI.
o Utilization of imaging modalities to guide therapeutic decision-making.
o Risk assessment models to identify high-risk NSTEMI patients who may benefit from aggressive intervention.

4. Pharmacologic Management Beyond Antithrombotics:
o Evolving roles of beta-blockers, ACE inhibitors, and statins in NSTEMI treatment regimens.
o Impact of novel lipid-lowering agents on post-NSTEMI outcomes.
o Strategies to address comorbidities such as diabetes and chronic kidney disease in NSTEMI patients.

5. Multidisciplinary Approaches and Patient-Centered Care:
o Integration of cardiology, emergency medicine, and primary care in managing NSTEMI.
o Development of personalized treatment plans based on patient preferences and clinical characteristics.
o Psychological and rehabilitation support to enhance recovery and quality of life post-NSTEMI.

6. Health Economics and Policy Implications:
o Cost-effectiveness analyses of different revascularization and antithrombotic strategies.
o Policy recommendations to improve access to advanced therapies and optimize resource utilization.
o Comparative studies on healthcare systems and their impact on NSTEMI patient outcomes.

This research topic is open to all article types aiming to elucidate the latest advances in revascularization and antithrombotic therapies for NSTEMI, providing a robust platform for scientific discourse and clinical innovation. Contributions to this collection will play a pivotal role in shaping future guidelines and therapeutic approaches, ultimately enhancing the management and prognosis of patients with non-ST elevation acute coronary syndromes.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

  • Brief Research Report
  • Case Report
  • Clinical Trial
  • Editorial
  • General Commentary
  • Methods
  • Mini Review
  • Opinion
  • Original Research

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Keywords: Non-ST Elevation Myocardial Infarction, Acute Coronary Syndromes, Percutaneous Coronary Intervention, Coronary Artery Bypass Grafting

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