About this Research Topic

Background

Orthostatic intolerance/tachycardia (OI/OT) has become an important issue for children, adolescent and young adults throughout the world. While it is primarily related to the instability of the autonomic nervous system in adolescence, but changes of lifestyle and mental health of current young people are also involved. In some cases, symptoms are triggered by a viral infection. Among patients with OI/OT, postural change causes headache, light headedness, brain fog, fatigue, palpitations, anxiety, or limited activity. If the symptoms are severe, the patients may become maladjusted to their society or become socially isolated which can have a negative impact on their physiological and mental health. Another notable recent topic is the onset of postural tachycardia syndrome, main part of OI/OT, as a symptom associated with long-COVID or following human papilloma vaccination. As such, OI/OT has become an increasing important topic for pediatricians.

Knowledge and treatment standards regarding OI/OT vary around the world. Even now, there are regions where this problem is so severe that people are struggling to figure out how to tackle it. On the other hand, there are countries where treatment is moving beyond pediatric care to areas such as multidisciplinary approach with professionals in both cardiology and rehabilitation.　Because it is known that OI/OT can occur along with Long COVID-19 or HPV vaccination, new research findings are available regularly. The inclusion of this issue as as a research topic will raise awareness and prompt further investigations. Consequently, standardization of management of children and adolescents with OI/OT will hopefully be achieved, leading in turn to improved outcomes.

Key elements of this special topic are as follows:

1) Prevalence of OI/PT in children and adolescents worldwide

2) Essential etiology of OI/OT

3) Aggravating factors of OI/OT in the daily life environment

4) Complications of OI, such as sleep disorders and psychiatric illness

5) Conservative and novelty pharmaceutical therapies

6) COVID19 related orthostatic tachycardia syndrome

7) Human papilloma vaccination and orthostatic tachycardia syndrome

8) Multidisciplinary approach for OI/OT

Discussion on research and clinical trials from all over the world will give us valuable information to improve outcome of OI/OT in children and adolescents.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• ... View all formats

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Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Review
• Study Protocol
• Systematic Review
• Technology and Code

Keywords: orthostatic intolerance, orthostatic hypotension, child, adolescent, deconditioning, long COVID, human papilloma virus vaccination, orthostatic tachycardia, postral tachycardia syndrome

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