Synthetic organic, bioorganic, medicinal, natural products and biomaterials chemistry are highly dynamic fields at the forefront of scientific innovation through creation of new molecules and materials with applications in chemical biology, biological sciences, and medicine. The integration of synthetic organic chemistry with biomedical applications has led to groundbreaking advancements in drug discovery, targeted precision medicine, new biomaterials for medical devices, etc. This Research Topic intends to compile dedicated articles to Professor Iwao Ojima, on the occasion of his 80th birthday, honoring his outstanding contributions to chemical sciences from organometallic chemistry and catalytic asymmetric synthesis to synthetic organic, medicinal and natural product chemistry at the interface of chemistry, biology and medicine.
This Research Topic aims to address the challenges in the development of highly efficient and selective methods and methodologies for the synthesis of a variety of unique organic molecules, which are crucial for advancing drug discovery, deciphering biological process, and biomedical applications. A key problem is the limited ability to create highly stereoselective and regioselective reactions under mild/green conditions. Recent advances in catalysis have shown promise in overcoming these limitations. By leveraging these advances, we should be able to enhance the precision of synthetic processes and optimize reaction times and yields. Additionally, the integration of computational chemistry and machine learning could optimize reaction conditions and predict outcomes, further streamlining the development of new therapeutic and diagnostic agents, as well as biomaterials. The goal is to capture innovative approaches to achieve highly efficient, sustainable and scalable chemical synthesis that can ultimately accelerate the translation of chemical discoveries into medical and industrial applications.
We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:
• New synthetic methods and methodologies for efficient synthesis of bioactive molecules
• Efficient synthesis of natural and unnatural bioactive compounds for therapy and diagnosis
• Catalysis and green chemistry for the development of therapeutics and diagnostic agents
• Synthetic chemistry applied to nanomedicine, nanoprobes, imaging and diagnostic tools
• Computational chemistry and machine learning applied to the optimization of chemical processes, relevant to biomedical applications
Greta Varchi was previously the co-founder of Theramol Srls and Kerline Srl. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Keywords:
Chemical synthesis, Catalysis, Green chemistry, Therapeutic/diagnostic agents, Biomedical applications
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Synthetic organic, bioorganic, medicinal, natural products and biomaterials chemistry are highly dynamic fields at the forefront of scientific innovation through creation of new molecules and materials with applications in chemical biology, biological sciences, and medicine. The integration of synthetic organic chemistry with biomedical applications has led to groundbreaking advancements in drug discovery, targeted precision medicine, new biomaterials for medical devices, etc. This Research Topic intends to compile dedicated articles to Professor Iwao Ojima, on the occasion of his 80th birthday, honoring his outstanding contributions to chemical sciences from organometallic chemistry and catalytic asymmetric synthesis to synthetic organic, medicinal and natural product chemistry at the interface of chemistry, biology and medicine.
This Research Topic aims to address the challenges in the development of highly efficient and selective methods and methodologies for the synthesis of a variety of unique organic molecules, which are crucial for advancing drug discovery, deciphering biological process, and biomedical applications. A key problem is the limited ability to create highly stereoselective and regioselective reactions under mild/green conditions. Recent advances in catalysis have shown promise in overcoming these limitations. By leveraging these advances, we should be able to enhance the precision of synthetic processes and optimize reaction times and yields. Additionally, the integration of computational chemistry and machine learning could optimize reaction conditions and predict outcomes, further streamlining the development of new therapeutic and diagnostic agents, as well as biomaterials. The goal is to capture innovative approaches to achieve highly efficient, sustainable and scalable chemical synthesis that can ultimately accelerate the translation of chemical discoveries into medical and industrial applications.
We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:
• New synthetic methods and methodologies for efficient synthesis of bioactive molecules
• Efficient synthesis of natural and unnatural bioactive compounds for therapy and diagnosis
• Catalysis and green chemistry for the development of therapeutics and diagnostic agents
• Synthetic chemistry applied to nanomedicine, nanoprobes, imaging and diagnostic tools
• Computational chemistry and machine learning applied to the optimization of chemical processes, relevant to biomedical applications
Greta Varchi was previously the co-founder of Theramol Srls and Kerline Srl. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Keywords:
Chemical synthesis, Catalysis, Green chemistry, Therapeutic/diagnostic agents, Biomedical applications
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.