Advancing Intervertebral Disc Degeneration Research: Focus on Annulus Fibrosus and Pain Management

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About this Research Topic

Submission deadlines

  1. Manuscript Submission Deadline 16 March 2025

  2. This Research Topic is still accepting articles.

Background

Intervertebral disc degeneration, particularly the pathology of the annulus fibrosus, is a critical area of research due to its significant impact on individuals' physical activity and quality of life. The annulus fibrosus, as the outer layer of the intervertebral disc, is essential for maintaining disc stability and function. Its degeneration is a major contributor to conditions such as disc herniation and chronic back pain, which are prevalent issues affecting a wide range of individuals, from athletes to the general population. Despite the availability of various treatment methods, their effectiveness is inconsistent, and recurrence rates remain high. Recent studies have begun to unravel the complex physiological and pathological mechanisms underlying annulus fibrosus degeneration, yet there remains a substantial gap in understanding the specific causes of pain and the development of comprehensive treatment strategies. Addressing these gaps is crucial for improving patient outcomes and enhancing the quality of life for those affected by disc-related issues.

This research topic aims to compile the latest advances in the field of intervertebral disc degeneration and annulus fibrosus research, with a particular focus on the interplay between disc health, chronic pain, and physical activity. By highlighting innovative treatment methods, rehabilitation techniques, and emerging technologies, this research topic seeks to promote academic exchange and foster interdisciplinary collaboration. The ultimate goal is to deepen the understanding of disc degeneration pathology and elevate treatment standards, not only for pain management but also for restoring disc function. Additionally, this research topic is dedicated to bridging the gap between basic theoretical research and clinical application, thereby providing more effective treatment options that enhance patients' ability to engage in physical activity and exercise more efficiently and comfortably.

To gather further insights into the complexities of intervertebral disc degeneration and annulus fibrosus pathology, we welcome articles addressing, but not limited to, the following themes:
- The impact of intervertebral disc degeneration and associated pain on sports performance and active living.
- The pathological mechanisms of intervertebral disc degeneration and the role of the annulus fibrosus.
- Innovative treatment strategies, rehabilitation techniques, and technologies for disc degeneration.
- Clinical case studies and treatment outcome evaluations.
- The application of gene therapy, biomaterials, and other emerging interventions in disc repair and pain reduction.
- Research outcomes from interdisciplinary and international collaborations, particularly in the context of sports, active living, and rehabilitation.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

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  • Case Report
  • Clinical Trial
  • Conceptual Analysis
  • Data Report
  • Editorial
  • General Commentary
  • Hypothesis and Theory
  • Methods

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Keywords: Intervertebral Disc Degeneration, Annulus Fibrosus, Treatment Methods, Injury repair

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Participating Journals

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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