About this Research Topic
Diseases such as cancer and tissue/organ failure have been one of the leading causes of mortality worldwide and their incidence continues to rise with the growing and aging global population. Therefore, there is a pressing need for rational and advanced therapies to improve therapeutic responses and tissue regeneration to prolong the survival of patients. Nanobiomaterials, which have appealing physicochemical properties, have been widely explored in disease treatment, especially in tumor therapy and tissue regeneration. However, challenges remain in integrating multimodal therapies that are highly efficacious, specific, and personalized.
The accelerated advancement of nanomedicine provides new platforms and techniques for high-efficient and safe combination therapies. The emergence of nano-based drug delivery systems has enabled new approaches for preferentially delivering theranostic agents to the disease sites, improving therapeutic targeting, reducing systemic toxicity, and overcoming multi-drug resistance. Furthermore, some multifunctional biomaterials have also shown a great ability to modulate the tumor and tissue micro-environment such as hypoxia, acidity, and redox, due to the special properties of the material itself. Therefore, these multifunctional biomaterials have great potential in integrating multimodal therapies to achieve optimal and synergetic combination therapies.
This Research Topic will focus on:
• the elaborate design and development of nanomaterials for cancer combination therapies;
• collecting research on unique approaches for cancer treatments based on multifunctional biomaterials;
• surmounting the current challenges in cancer treatment and explore the novel application of biomaterials in cancer theranostics;
• providing new sights and promising strategies for cancer combination therapies, as well as tissue regeneration and repair, to advance the development and clinical application of nanomaterials.
The accelerated advancement of nanomedicine provides new platforms and techniques for high-efficient and safe combination therapies. The emergence of nano-based drug delivery systems has enabled new approaches for preferentially delivering theranostic agents to the disease sites, improving therapeutic targeting, reducing systemic toxicity, and overcoming multi-drug resistance. Furthermore, some multifunctional biomaterials have also shown a great ability to modulate the tumor and tissue micro-environment such as hypoxia, acidity, and redox, due to the special properties of the material itself. Therefore, these multifunctional biomaterials have great potential in integrating multimodal therapies to achieve optimal and synergetic combination therapies.
This Research Topic will focus on:
• the elaborate design and development of nanomaterials for cancer combination therapies;
• collecting research on unique approaches for cancer treatments based on multifunctional biomaterials;
• surmounting the current challenges in cancer treatment and explore the novel application of biomaterials in cancer theranostics;
• providing new sights and promising strategies for cancer combination therapies, as well as tissue regeneration and repair, to advance the development and clinical application of nanomaterials.
Keywords: Biomaterials, Nanodrugs, Cancer, Regeneration, Tissue Repair
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