About this Research Topic
Accumulation of tau leads to neuroinflammation and neuronal cell death in tauopathies, including Alzheimer’s disease. Growing evidence suggests critical involvement of lipid dyshomeostasis in pathogenesis of tauopathies. However, the role of tau aggregates in regulating lipid metabolism and the role of lipid in tau accumulation remain less characterized and poorly understood.
Understanding the lipid-tau relationship is of paramount importance given the increasing prevalence of tauopathies and the current lack of effective treatments. Lipids are fundamental to cellular structures and signaling pathways, and their dysregulation can significantly impact neuronal function and survival. This topic seeks to explore these multifaceted relationships, using cutting-edge technologies and methodologies to provide a comprehensive understanding of the lipid-tau interplay.
This topic aims to uncover the multifaceted relationships between lipids and tauopathies, highlighting both mechanistic insights and therapeutic opportunities. We aim to shed light on the underlying mechanisms and provide insights into the diagnosis, management, and treatment of tauophies. By encouraging the application of novel technologies and methods for detecting the roles of lipids in tauopathies, we hope to drive forward our understanding of these diseases.
This Research Topic welcomes various article types, including original research articles, reviews, mini-reviews, systematic reviews, clinical trials, case reports, perspectives, short communications as well as study protocols relevant to this topic. Topics of interest include but are not limited to:
- How lipid metabolism affects tau accumulation
- Characteristics of lipid metabolism changes in tauopathies.
- The role of tau protein in lipid metabolism.
- Mechanisms underlying the relationship between lipid and protein signaling in in tauopathies
By bringing together leading experts in lipid metabolism, neuroscience, and related fields, this Research Topic aims to foster collaborative efforts to tackle the complex interplay between lipids and tau proteins. The insights gained could pave the way for innovative therapeutic strategies and improve clinical outcomes for patients suffering from tauopathies.
Understanding the lipid-tau relationship is of paramount importance given the increasing prevalence of tauopathies and the current lack of effective treatments. Lipids are fundamental to cellular structures and signaling pathways, and their dysregulation can significantly impact neuronal function and survival. This topic seeks to explore these multifaceted relationships, using cutting-edge technologies and methodologies to provide a comprehensive understanding of the lipid-tau interplay.
This topic aims to uncover the multifaceted relationships between lipids and tauopathies, highlighting both mechanistic insights and therapeutic opportunities. We aim to shed light on the underlying mechanisms and provide insights into the diagnosis, management, and treatment of tauophies. By encouraging the application of novel technologies and methods for detecting the roles of lipids in tauopathies, we hope to drive forward our understanding of these diseases.
This Research Topic welcomes various article types, including original research articles, reviews, mini-reviews, systematic reviews, clinical trials, case reports, perspectives, short communications as well as study protocols relevant to this topic. Topics of interest include but are not limited to:
- How lipid metabolism affects tau accumulation
- Characteristics of lipid metabolism changes in tauopathies.
- The role of tau protein in lipid metabolism.
- Mechanisms underlying the relationship between lipid and protein signaling in in tauopathies
By bringing together leading experts in lipid metabolism, neuroscience, and related fields, this Research Topic aims to foster collaborative efforts to tackle the complex interplay between lipids and tau proteins. The insights gained could pave the way for innovative therapeutic strategies and improve clinical outcomes for patients suffering from tauopathies.
Keywords: therapeutic potential, lipid metabolism, lipid signaling, tauopathies, propagation of pathology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
