Cancer Epidemiology and Etiology Evaluation in Latin American Population

Latin America, characterized by its unique genetic makeup and diverse environmental and lifestyle factors, is experiencing a growing cancer burden as its population ages. Differences in cancer susceptibility, treatment responses, and progression rates compared to other populations highlight the importance of the region’s unique genetic ancestry—a mix of Native American, European, and Sub-Saharan African elements. This mixed heritage forms a complex molecular landscape ripe for groundbreaking research that could drive advancements in understanding cancer’s nuances.

This Research Topic aims to delve deep into the molecular characterization of cancers prevalent in Latin America, utilizing state-of-the-art technologies such as next-gen sequencing, single-cell RNA sequencing, and liquid biopsies. Our goal is to unearth distinctive molecular patterns and biomarkers that could potentially revolutionize diagnosis, prognosis, and treatment specifically tailored for the Latin American demographic, thereby addressing disease heterogeneity and improving precision medicine in the region.

This topic covers a wide range of studies that stretch from epidemiological reviews to advanced molecular analysis, aiming to bridge the gap between experimental research and clinical implementation in Latin America:

- Epidemiological studies on cancer incidence, prevalence, and risk factors specific to Latin America
- Research focusing on the genetic ancestry influences on cancer development
- Identification and validation of new biomarkers for better diagnostic and prognostic strategies
- Translational research endeavors that link laboratory findings to bedside applications
- Novel therapeutic approaches aimed at specific molecular pathways relevant to the Latin American genetic context
- Utilization of AI and machine learning to enhance research on cancer in Latin America

Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases that are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Systematic Review
• Technology and Code

Keywords: Neoplasms, Latin America, Molecular Diagnostic Techniques, Ancestry, Health Disparities

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.