In the historical context, psychedelics reveal a spectrum of applications, ranging from spiritual and recreational use to effects on the central nervous system and the expansion of consciousness. The literature has shown increasing interest in the potential therapeutic benefits of psychedelic substances in the treatment of neurological diseases. Psychedelics can interact with serotonin and MAO receptors in the brain, promoting neuroplasticity and potentially relieving symptoms of several neurological disorders.
Recent clinical trials have shown promise in using these substances to treat conditions such as depression, anxiety, post-traumatic stress disorder, and even neurodegenerative diseases such as Alzheimer's and Parkinson's. Therefore, investigating the pharmacological basis of psychedelic action, analyzing results from preclinical and clinical research, and discussing future directions and challenges in integrating psychedelics into conventional medical practice is critical. Additionally, since it is crucial to understand the risks associated with the abusive and recreational use of psychedelics, articles on toxicity and the legal ramifications of psychedelic use are welcome.
This research topic aims to provide insights into the fundamental mechanisms of action of psychedelics, their historical and contemporary uses, and the emerging evidence supporting their efficacy in clinical settings. By understanding these aspects, we can explore the potential therapeutic benefits of psychedelics in treating various neurological diseases and neuroinflammation. Moreover, investigating their impact on neural circuits, brain plasticity, and inflammatory pathways could pave the way for new treatments for these challenging disorders. Additionally, this topic should also address the abusive and recreational use of psychedelic substances and the consequences for therapeutic application.
- Detailed exploration of how psychedelic substances interact with neural pathways, receptors and neuroinflammation.
- Investigations using cells cultures and animal models to understand the effects of psychedelics.
- Psychedelic therapy in neurological disorders and neuroinflammation, including case studies, meta-analyses, and systematic reviews.
- Promote insights into the abusive and recreational use of psychedelics and their health consequences.
- Historical context and contemporary applications of psychedelics in medicine, including regulatory challenges and changes in public perception.
By addressing these themes researchers can advance in understanding of the role of psychedelic substances in the treatment of neurological diseases and neuroinflammation and pave the way for new therapeutic approaches. Additionally, data on the abusive and recreational use of psychedelics can help understand the legal consequences of a potential therapeutic use.
Researchers can contribute to the following types of manuscripts of interest:
- Original Research Articles
- Review Articles
- Case Reports
- Short Communications
- Opinion and Perspective Pieces
- Clinical Trial Reports
Keywords:
entheogen, oxidative stress, inflammation, neurological disease, psychoactive compounds, neural circuitry, hallucinogens
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
In the historical context, psychedelics reveal a spectrum of applications, ranging from spiritual and recreational use to effects on the central nervous system and the expansion of consciousness. The literature has shown increasing interest in the potential therapeutic benefits of psychedelic substances in the treatment of neurological diseases. Psychedelics can interact with serotonin and MAO receptors in the brain, promoting neuroplasticity and potentially relieving symptoms of several neurological disorders.
Recent clinical trials have shown promise in using these substances to treat conditions such as depression, anxiety, post-traumatic stress disorder, and even neurodegenerative diseases such as Alzheimer's and Parkinson's. Therefore, investigating the pharmacological basis of psychedelic action, analyzing results from preclinical and clinical research, and discussing future directions and challenges in integrating psychedelics into conventional medical practice is critical. Additionally, since it is crucial to understand the risks associated with the abusive and recreational use of psychedelics, articles on toxicity and the legal ramifications of psychedelic use are welcome.
This research topic aims to provide insights into the fundamental mechanisms of action of psychedelics, their historical and contemporary uses, and the emerging evidence supporting their efficacy in clinical settings. By understanding these aspects, we can explore the potential therapeutic benefits of psychedelics in treating various neurological diseases and neuroinflammation. Moreover, investigating their impact on neural circuits, brain plasticity, and inflammatory pathways could pave the way for new treatments for these challenging disorders. Additionally, this topic should also address the abusive and recreational use of psychedelic substances and the consequences for therapeutic application.
- Detailed exploration of how psychedelic substances interact with neural pathways, receptors and neuroinflammation.
- Investigations using cells cultures and animal models to understand the effects of psychedelics.
- Psychedelic therapy in neurological disorders and neuroinflammation, including case studies, meta-analyses, and systematic reviews.
- Promote insights into the abusive and recreational use of psychedelics and their health consequences.
- Historical context and contemporary applications of psychedelics in medicine, including regulatory challenges and changes in public perception.
By addressing these themes researchers can advance in understanding of the role of psychedelic substances in the treatment of neurological diseases and neuroinflammation and pave the way for new therapeutic approaches. Additionally, data on the abusive and recreational use of psychedelics can help understand the legal consequences of a potential therapeutic use.
Researchers can contribute to the following types of manuscripts of interest:
- Original Research Articles
- Review Articles
- Case Reports
- Short Communications
- Opinion and Perspective Pieces
- Clinical Trial Reports
Keywords:
entheogen, oxidative stress, inflammation, neurological disease, psychoactive compounds, neural circuitry, hallucinogens
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.