The pediatrics period is a critical time during which many diseases, particularly rare ones, emerge. However, research on therapeutic strategies for children is limited due to the rarity of these conditions and the perception that pediatric patients are more fragile than adults. Consequently, treatments are often approved for adults first, without fully understanding their efficacy and safety in children. Additionally, diagnostic methods for children are sometimes more restricted compared to adults, either due to potential adverse effects or the challenge of correlating results to a pediatric sample. This situation underscores the urgent need for more research focused on pediatric therapies, especially for rare diseases. Emerging approaches, such as targeted therapies and orphan drugs show promise, but their pediatric applications require thorough investigation. Advances in pediatric-specific diagnostic techniques could also enhance early detection and disease management. Addressing these challenges can lead to more effective and safer treatments for children, improving overall health outcomes.
To date, the range of therapeutic and diagnostic options available for use in pediatric care is becoming increasingly broad. More and more treatments, initially intended only for adults, are finding extensive application in pediatrics, alongside the development of new diagnostic techniques that allow for early detection of diseases or the discovery of their underlying molecular mechanisms. This naturally correlates with a significant increase in pediatric patients being subjected to treatments whose benefits or side effects may not yet be fully understood, as well as the potential correlations with other conditions that may arise in childhood and possible new applications. Additionally, the increasingly early diagnosis of diseases that develop in childhood can revolutionize the follow-up and subsequent treatment of these conditions, altering the natural course of the disease as we know it today. For this reason, we want to evaluate the latest scientific advancements regarding the use of new therapeutic strategies in clinical practice, particularly targeted therapies and orphan drugs and how they impact pediatric patients. This initiative seeks to foster a deeper understanding of the evolving landscape in pediatric therapeutics and diagnostics, ultimately aiming to enhance health outcomes for children.
Potential themes:
- Biologic drugs
- Targeted therapies
- Benefits and risks of new management strategies
- Advances in molecular diagnosis
- New diagnostic strategies
We are interested in a range of article types including Original Research, Review, Mini Review, Case Report and more. A full list of accepted articles can be found in the 'about journal' tab.
Keywords:
pediatrics; targeted therapies; molecular; diagnostic advances; treatment; biologic drugs; children; adolescent
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
The pediatrics period is a critical time during which many diseases, particularly rare ones, emerge. However, research on therapeutic strategies for children is limited due to the rarity of these conditions and the perception that pediatric patients are more fragile than adults. Consequently, treatments are often approved for adults first, without fully understanding their efficacy and safety in children. Additionally, diagnostic methods for children are sometimes more restricted compared to adults, either due to potential adverse effects or the challenge of correlating results to a pediatric sample. This situation underscores the urgent need for more research focused on pediatric therapies, especially for rare diseases. Emerging approaches, such as targeted therapies and orphan drugs show promise, but their pediatric applications require thorough investigation. Advances in pediatric-specific diagnostic techniques could also enhance early detection and disease management. Addressing these challenges can lead to more effective and safer treatments for children, improving overall health outcomes.
To date, the range of therapeutic and diagnostic options available for use in pediatric care is becoming increasingly broad. More and more treatments, initially intended only for adults, are finding extensive application in pediatrics, alongside the development of new diagnostic techniques that allow for early detection of diseases or the discovery of their underlying molecular mechanisms. This naturally correlates with a significant increase in pediatric patients being subjected to treatments whose benefits or side effects may not yet be fully understood, as well as the potential correlations with other conditions that may arise in childhood and possible new applications. Additionally, the increasingly early diagnosis of diseases that develop in childhood can revolutionize the follow-up and subsequent treatment of these conditions, altering the natural course of the disease as we know it today. For this reason, we want to evaluate the latest scientific advancements regarding the use of new therapeutic strategies in clinical practice, particularly targeted therapies and orphan drugs and how they impact pediatric patients. This initiative seeks to foster a deeper understanding of the evolving landscape in pediatric therapeutics and diagnostics, ultimately aiming to enhance health outcomes for children.
Potential themes:
- Biologic drugs
- Targeted therapies
- Benefits and risks of new management strategies
- Advances in molecular diagnosis
- New diagnostic strategies
We are interested in a range of article types including Original Research, Review, Mini Review, Case Report and more. A full list of accepted articles can be found in the 'about journal' tab.
Keywords:
pediatrics; targeted therapies; molecular; diagnostic advances; treatment; biologic drugs; children; adolescent
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.