About this Research Topic
Metabolism and inflammation are biological processes that play vital roles in our survival. Metabolism controls energy utilization, while inflammation handles defense and repair. Both respond to stressors to restore the organism’s homeostasis, and their interplay plays a crucial role in balancing health or disease. Nowadays, it is widely accepted that understanding and targeting immunometabolism is critical for developing novel preventive and therapeutic approaches for diseases such as cardio-renal, hepatic diseases, rheumatic diseases, or allergic diseases. In this regard, many hormones and/or their analogs are currently being tested in pre-clinical and clinical trials for different pathologies. These pathologies are related to metabolic and/or inflammatory deregulation and include the growth hormone, ghrelin, fibroblast growth factor-21 (FGF-21), and new relaxin-2 analogs, among many others.
This Research Topic is focused on the use of hormones or their synthetic analogs as therapeutic agents for diseases with a basis in metabolic and/or inflammatory disruptions and aimed at further understanding of:
• Using endogenous hormones or synthetic analogs as therapeutic agents in metabolic and inflammatory diseases.
• Potential new applications or therapeutic uses in metabolic and inflammatory diseases of commercialized hormones.
• A deeper understanding of the mechanisms through which endogenous hormones can modulate immunometabolism.
We welcome both original research and Review articles.
Editors Dr. Sandra Feijóo Bandín and Alana Aragón Herrera received financial support from Bayer for the development of a research project. The other Topic Editors declare no competing interests concerning the Research Topic subject.
Keywords: Metabolism, Hormones, Inflammation, Immunometabolism, Therapeutic Use
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.