About this Research Topic
Cancer is a complex and multifaceted disease characterized by the uncontrolled growth and spread of abnormal cells. It can affect virtually any part of the body, leading to various forms such as lung, prostate, liver and colorectal cancer etc. Symptoms vary widely depending on the type and stage of cancer, often making early detection challenging. The current treatment options include surgery, chemotherapy, radiation therapy, and emerging modalities like immunotherapy and targeted therapy. Despite advances in medical research, cancer remains a leading cause of mortality worldwide, necessitating ongoing efforts for improved prevention, diagnosis, and treatment.
Nanotechnology-based delivery systems have emerged as a promising approach to enhance the efficacy and specificity of cancer therapies while minimizing adverse effects. These systems leverage nanoparticles' unique properties to target cancer cells precisely, improve drug solubility, and control drug release. These particles can be engineered to recognize and bind to specific biomarkers present on cancer cells. This targeted approach ensures that therapeutic agents are concentrated at the tumor site, sparing healthy tissues from exposure and reducing systemic toxicity.
Furthermore, nanotechnology enables the development of multifunctional nanoparticles that can carry multiple therapeutic agents or combine therapeutic and diagnostic functions (theranostics). These nanoparticles can deliver chemotherapy drugs, gene therapy vectors, or immunotherapeutic agents simultaneously, providing a synergistic effect that enhances treatment outcomes. Additionally, incorporating imaging agents allows for real-time monitoring of drug delivery and treatment response, facilitating personalized and adaptive treatment strategies.
Therefore, this Research Topic aims to provide a comprehensive, contemporary collection of research focusing on exploring nanotechnology-based delivery systems for cancer treatment. We welcome Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data notes, and technical notes, but are not limited to the following:
• Develop nanoparticles that can selectively bind to cancer-specific biomarkers to improve targeting accuracy and reduce off-target effects.
• Investigate the potential of multifunctional nanoparticles capable of carrying multiple therapeutic agents or combining therapy with diagnostic imaging (theranostics).
• Assess the biocompatibility and long-term safety of various nanomaterials used in drug delivery systems to ensure they do not induce adverse immune responses or toxicity.
• Enhance the solubility and bioavailability of poorly soluble anticancer drugs through nanoparticle encapsulation to improve therapeutic efficacy.
• Integrate imaging agents into nanoparticles to allow for real-time tracking of drug delivery and treatment response, enabling more precise and adaptive treatment strategies.
Nanotechnology-based delivery systems have emerged as a promising approach to enhance the efficacy and specificity of cancer therapies while minimizing adverse effects. These systems leverage nanoparticles' unique properties to target cancer cells precisely, improve drug solubility, and control drug release. These particles can be engineered to recognize and bind to specific biomarkers present on cancer cells. This targeted approach ensures that therapeutic agents are concentrated at the tumor site, sparing healthy tissues from exposure and reducing systemic toxicity.
Furthermore, nanotechnology enables the development of multifunctional nanoparticles that can carry multiple therapeutic agents or combine therapeutic and diagnostic functions (theranostics). These nanoparticles can deliver chemotherapy drugs, gene therapy vectors, or immunotherapeutic agents simultaneously, providing a synergistic effect that enhances treatment outcomes. Additionally, incorporating imaging agents allows for real-time monitoring of drug delivery and treatment response, facilitating personalized and adaptive treatment strategies.
Therefore, this Research Topic aims to provide a comprehensive, contemporary collection of research focusing on exploring nanotechnology-based delivery systems for cancer treatment. We welcome Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data notes, and technical notes, but are not limited to the following:
• Develop nanoparticles that can selectively bind to cancer-specific biomarkers to improve targeting accuracy and reduce off-target effects.
• Investigate the potential of multifunctional nanoparticles capable of carrying multiple therapeutic agents or combining therapy with diagnostic imaging (theranostics).
• Assess the biocompatibility and long-term safety of various nanomaterials used in drug delivery systems to ensure they do not induce adverse immune responses or toxicity.
• Enhance the solubility and bioavailability of poorly soluble anticancer drugs through nanoparticle encapsulation to improve therapeutic efficacy.
• Integrate imaging agents into nanoparticles to allow for real-time tracking of drug delivery and treatment response, enabling more precise and adaptive treatment strategies.
Keywords: Cancer, Nanoparticle, Anti-cancer, Nanocarrier, Nano-drug delivery systems
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
