About this Research Topic
This special Research Topic in Frontiers delves into the exploration of biomarkers in trauma and critical care, with a particular emphasis on cellular and vesicular biomarkers connected to immunity. This encompassing topic aims to investigate specific markers that can serve as indicators of trauma severity, potential complications, and prognosis, taking into consideration the crucial role of host immunity in responding to traumatic injuries.
Trauma, being a leading of death globally, particularly young patients, underscores the importance of understanding the intricate interplay between the immune system and trauma outcomes. While there are unspecific various biomarkers related to trauma, such as albumin, creatinine kinase, and cytokines, emerging evidence of current research suggests that microRNAs and extracellular vesicles hold promise in detecting trauma-related changes more specifically. These markers, detectable in body fluids like blood, urine, and cerebrospinal fluid, offer a non-invasive means to assess trauma impact, yet the immune compartment remains underexplored in this context.
By directing focus towards novel markers encompassing cellular, metabolic, and vesicular components, the research community aims to unveil the immune system's intricate involvement in traumatic injuries. Through this exploration, the objective is to develop refined strategies for risk assessment, tailored treatment approaches, and timely surgical interventions to optimize outcomes for individuals affected by severe trauma.
In summary, this special research topic advances the scientific community's understanding of biomarkers in trauma and care, underscoring the essential role of cellular and vesicular markers as key elements in the landscape of trauma research and clinical management, while emphasizing the vital contribution of host immunity in shaping responses to traumatic insults.
*****Please note that manuscripts where the main focus is not on research dealing with immunity and its mechanisms are out of scope for this research topic****
The Research Topic Editors declare that they have no conflicts of interest in relation to the editorship of this collection.
Trauma, being a leading of death globally, particularly young patients, underscores the importance of understanding the intricate interplay between the immune system and trauma outcomes. While there are unspecific various biomarkers related to trauma, such as albumin, creatinine kinase, and cytokines, emerging evidence of current research suggests that microRNAs and extracellular vesicles hold promise in detecting trauma-related changes more specifically. These markers, detectable in body fluids like blood, urine, and cerebrospinal fluid, offer a non-invasive means to assess trauma impact, yet the immune compartment remains underexplored in this context.
By directing focus towards novel markers encompassing cellular, metabolic, and vesicular components, the research community aims to unveil the immune system's intricate involvement in traumatic injuries. Through this exploration, the objective is to develop refined strategies for risk assessment, tailored treatment approaches, and timely surgical interventions to optimize outcomes for individuals affected by severe trauma.
In summary, this special research topic advances the scientific community's understanding of biomarkers in trauma and care, underscoring the essential role of cellular and vesicular markers as key elements in the landscape of trauma research and clinical management, while emphasizing the vital contribution of host immunity in shaping responses to traumatic insults.
*****Please note that manuscripts where the main focus is not on research dealing with immunity and its mechanisms are out of scope for this research topic****
The Research Topic Editors declare that they have no conflicts of interest in relation to the editorship of this collection.
Keywords: Biomarkers, Immunity, Cellular, Vascular, Trauma
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
