The increasing prevalence of affective disorders among children and adolescents, such as depression, anxiety disorders, and bipolar disorder, has become a significant concern. Factors like social pressure and the fast pace of modern life contribute to this rise, impacting young people's personal development, academic performance, social skills, and family relationships.
Neuroimaging studies have identified abnormalities in brain structure, function, and metabolism in specific brain regions associated with affective disorders. However, findings are inconsistent, indicating a need for further research. Chronic stress, a significant factor in emotional dysregulation, may alter brain structures and functions, particularly in regions linked to emotional and cognitive control like the amygdala and prefrontal cortex. These structural and functional changes can contribute to the development of emotional disorders, including anxiety and depression.
This Research Topic aims to investigate the pathogenesis of adolescent affective disorders using neuroimaging techniques, including magnetoencephalography (MEG), electroencephalography (EEG), event-related potentials (ERP), and functional magnetic resonance imaging (fMRI). These studies are particularly focused on the imbalance between the monoamine system and the cholinergic system, with an emphasis on the role of monoamine neurotransmitters.
Understanding the neural mechanisms underlying these disorders is crucial for early identification and intervention. In addition, this Research Topic seeks to evaluate the efficacy of psychotherapy and physical therapy for young individuals with affective disorders. Psychosocial interventions, such as cognitive-behavioral therapy (CBT), are highlighted for their potential in helping adolescents develop healthier coping mechanisms with minimal adverse effects. This comprehensive approach aims to provide a scientific basis for improving mental health outcomes for affected children and adolescents.
In summary, adolescent affective disorder is a multifactorial and multidimensional problem that requires the integrated use of basic and clinical research findings, along with multidisciplinary and multifaceted interventions, to promote full recovery. Meanwhile, we call on society, schools, and families to provide more support and understanding for children and adolescents with affective disorders.
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Brief Research Report
Case Report
Clinical Trial
Community Case Study
Conceptual Analysis
Data Report
Editorial
FAIR² Data
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Article types
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
Brief Research Report
Case Report
Clinical Trial
Community Case Study
Conceptual Analysis
Data Report
Editorial
FAIR² Data
FAIR² DATA Direct Submission
General Commentary
Hypothesis and Theory
Methods
Mini Review
Opinion
Original Research
Perspective
Registered Report
Review
Study Protocol
Systematic Review
Technology and Code
Keywords: Pathogenesis, Children and Adolescents, Monoamine Neurotransmitters, Affective Disorders, Neuroimaging, Monoamine System, Cholinergic System, Interventions
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