About this Research Topic
With the acceleration of global integration, the rapid development of population mobility and international trade, as well as the frequent occurrence of public health events such as sudden infectious diseases and foodborne illnesses, health issues have become increasingly complex. In response to these challenges, the concept of "one health" has emerged and gained global prominence, particularly since the outbreak of COVID-19. Ruminant animals like cattle and sheep not only provide high-quality meat, milk, fur, and other valuable products but also have significant implications for human health. However, this close relationship also entails potential risks associated with the transmission of disease-causing microorganisms such as bacteria and viruses between humans and ruminants. For instance, the recent worldwide resurgence of avian influenza H5N1 has raised public concerns due to its confirmed transmission from farms to humans for the first time.
In this topic, we focus on pathogenic microorganisms that can cause infections in both humans and ruminants under the same health concept, such as E. coli and Bacillus cereus. These microorganisms are responsible for mastitis in dairy cows and diarrhea in humans. Notably, pasteurization does not eliminate Bacillus cereus from milk, significantly increasing the risk of human infection. Adaptive immune responses play a crucial role as the "last line of defense" against these pathogens in both humans and ruminants. The quantitative traits of cellular and humoral mediated immune responses in ruminants can be utilized to estimate breeding values and have been applied to breed high-immunity dairy cows successfully. While extensive research has been conducted on adaptive immunity in humans, there is a wealth of reference points available for researchers working within the field of ruminant health. This project aims to address complex health issues holistically by considering the interconnectedness between humans, ruminants, and their environment through zoonosis studies and comparative medical research - exploring commonalities as well as distinctive characteristics of adaptive immune responses induced by infections.
Suitable subtopics for this Research Topic are included and listed below, but not limited to:
1. Epidemiological study investigating the transmission of infectious diseases between ruminant animals and humans.
2. Identification and characterization of trait markers associated with adaptive immune responses in ruminant species, providing insights into assessing human immunity.
3. The interactions between hosts and pathogenic microorganisms that have the ability to infect both humans and ruminants, particularly focusing on the host T cell and B cell responses to these pathogens.
The Research Topic Editors confirm that they have no conflicts of interest to declare in relation to the editorship of this collection.
In this topic, we focus on pathogenic microorganisms that can cause infections in both humans and ruminants under the same health concept, such as E. coli and Bacillus cereus. These microorganisms are responsible for mastitis in dairy cows and diarrhea in humans. Notably, pasteurization does not eliminate Bacillus cereus from milk, significantly increasing the risk of human infection. Adaptive immune responses play a crucial role as the "last line of defense" against these pathogens in both humans and ruminants. The quantitative traits of cellular and humoral mediated immune responses in ruminants can be utilized to estimate breeding values and have been applied to breed high-immunity dairy cows successfully. While extensive research has been conducted on adaptive immunity in humans, there is a wealth of reference points available for researchers working within the field of ruminant health. This project aims to address complex health issues holistically by considering the interconnectedness between humans, ruminants, and their environment through zoonosis studies and comparative medical research - exploring commonalities as well as distinctive characteristics of adaptive immune responses induced by infections.
Suitable subtopics for this Research Topic are included and listed below, but not limited to:
1. Epidemiological study investigating the transmission of infectious diseases between ruminant animals and humans.
2. Identification and characterization of trait markers associated with adaptive immune responses in ruminant species, providing insights into assessing human immunity.
3. The interactions between hosts and pathogenic microorganisms that have the ability to infect both humans and ruminants, particularly focusing on the host T cell and B cell responses to these pathogens.
The Research Topic Editors confirm that they have no conflicts of interest to declare in relation to the editorship of this collection.
Keywords: Ruminant, Adaptive immune responses, Infection, Vaccine, Immunity Marker
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