About this Research Topic
Antimicrobial resistance (AMR) and multidrug resistance (MDR) development has become a significant issue in recent years. Particularly, in clinical settings, following the changed medical practices enforced during COVID-19 pandemic, and increased use of antimicrobial medication, may have caused increased AMR occurrences.
However, the veterinary sector is a significantly bigger category compared to clinical settings. It is estimated that more than two-thirds of the global antimicrobial drugs usage is in veterinary settings. As veterinary animals, such as cattle, poultry and fishery, significantly contribute to human food and nutrition, it is expected that the AMR and MDR development amongst this cohort, horizontally or vertically, would impact the whole animal related food products.
Particularly, the gastrointestinal tract gets a direct, and highest impact of AMR and MDR development, as microbiome composition, and therefore, behavior changes significantly. These changes have been observed to cause several downstream effects.
Currently there is a knowledge gap relating to mechanisms of gut microbiome perturbation due to AMR and MDR development. The understanding of these mechanisms also will pave a way for developing novel mitigation strategies for tackling these issues and increasing the gut microbiome resilience to these incidents.
The areas of submissions are broad, and include clinical, veterinary, food and nutrition, as well as the pharmaceutical sector. We accept manuscripts related, but not limited to, the following areas of interest:
1. The use of antimicrobials (AM) has a major impact on gut microbiota.
2. The gut microbiota, under the selective pressure of AM, becomes a hotspot for AMR gene exchange.
3. The development of gut resistome and associated AMR spread to other ecological niches.
4. The interaction between environmental resistome and gut resistome and related AMR.
5. The raising administration of AMs in animals’ food critically affects the agriculture and boosts AMR gene exchange hot spots and related dissemination processes.
In this Research Topic we welcome the following article types: Methods, Mini Review, Opinion, Original Research, Perspective, Review, Systematic Review.
However, the veterinary sector is a significantly bigger category compared to clinical settings. It is estimated that more than two-thirds of the global antimicrobial drugs usage is in veterinary settings. As veterinary animals, such as cattle, poultry and fishery, significantly contribute to human food and nutrition, it is expected that the AMR and MDR development amongst this cohort, horizontally or vertically, would impact the whole animal related food products.
Particularly, the gastrointestinal tract gets a direct, and highest impact of AMR and MDR development, as microbiome composition, and therefore, behavior changes significantly. These changes have been observed to cause several downstream effects.
Currently there is a knowledge gap relating to mechanisms of gut microbiome perturbation due to AMR and MDR development. The understanding of these mechanisms also will pave a way for developing novel mitigation strategies for tackling these issues and increasing the gut microbiome resilience to these incidents.
The areas of submissions are broad, and include clinical, veterinary, food and nutrition, as well as the pharmaceutical sector. We accept manuscripts related, but not limited to, the following areas of interest:
1. The use of antimicrobials (AM) has a major impact on gut microbiota.
2. The gut microbiota, under the selective pressure of AM, becomes a hotspot for AMR gene exchange.
3. The development of gut resistome and associated AMR spread to other ecological niches.
4. The interaction between environmental resistome and gut resistome and related AMR.
5. The raising administration of AMs in animals’ food critically affects the agriculture and boosts AMR gene exchange hot spots and related dissemination processes.
In this Research Topic we welcome the following article types: Methods, Mini Review, Opinion, Original Research, Perspective, Review, Systematic Review.
Keywords: AMR, MDR, gut dysbiosis, microbiome, systems biology, mitigation, treatment, mechanism of action
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
