Bioresorbable Materials: What is New?

The continuous quest to deal with numerous medical conditions leads to the development of various materials capable of meeting specific demands. From the aspects of internally administrated materials, one of these demands which stands out is bioresorption. As a part of the three bio- (biocompatible, biodegradable, and bioresorbable), it represents the ability of a material to be decomposed and absorbed by the body on a molecular level within physiological processes. It is often considered equal to biodegradation since these two processes are usually inseparable. When selecting and designing implantable materials multiple factors, including mechanical properties, non-toxicity, surface alterations, degradation kinetics, and corrosion resistance, must be reviewed.

Over the past few decades, significant progress has been achieved in the development of bioresorbable materials encompassing ceramics, glasses, polymers, and metallic materials. These materials are developing to degrade or be resorbed within the body rather than requiring surgical removal, thereby minimizing the risk of tissue damage or infection.

When it comes to electrical and sensing components, bioresorbable materials are constantly promoted due to the functioning within physiological conditions for a predetermined duration before dissolving completely in vivo, interaction with organs, tissues, and biofluids in real-time gathering clinical data, delivering customized therapeutics based on disease progression and patient needs.

The advanced generations of bio-implantable materials aimed at tissue repair and regeneration, or medical devices will require enhanced control of the interaction on the interface with the surrounding tissue. Additionally, there is a need for refining the mechanical properties and degradation/resorption profiles of these materials to expand their applicability and enhance clinical outcomes. These are some of the issues that will be addressed in the research topic ''Bioresorbable Materials: What is New?''.

This Research Topic is devoted to cutting-edge advancements in the field of bioresorbable materials, their latest developments, breakthroughs, and applications. We welcome original research articles, mini-reviews, and reviews encompassing, but not limited to the following topics:

- Novel materials designed to degrade and resorbed over time, offering promising applications in medical implants, drug delivery systems, and tissue engineering;

- Innovations in materials engineering for implants, prosthetics, and medical devices to enhance biocompatibility, durability, and performance;

- Advances in designing and fabrication of functional tissues and organs using versatile materials to address regenerative medicine challenges;

- Development of materials and technologies for real-time monitoring of biological parameters, disease diagnosis, and therapeutic interventions;

- New insights in the interaction between materials and biological environment (including body fluids, proteins, cells) during degradation/resorption: effects on materials properties and functionalities.