Frontiers | Insights in Experimental Pharmacology and Drug Discovery: 2024

Insights in Experimental Pharmacology and Drug Discovery: 2024

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ORIGINAL RESEARCH

Accepted on 06 Feb 2025

Ursodeoxycholic and chenodeoxycholic bile acids alleviate endotoxininduced acute lung injury in rats by modulating aquaporin expression and pathways associated with apoptosis and inflammation

Tatjana Milivojac
Milkica Grabež
Ljiljana Amidžić
Alma Prtina
Aleksandra Krivokuća
Uglješa Maličević
Maja Barudžija
Milka Matičić
Snežana Uletilović
8 more
Ranko Škrbić

doi 10.3389/fphar.2025.1484292

ORIGINAL RESEARCH

Accepted on 21 Jan 2025

Melatonin protects retinal pigment epithelium cells against ferroptosis in AMD via the PI3K/AKT/MDM2/P53 pathway

Ping Wu
Long Zhao
Yong Du
Jing Lu
Yuxia He
Qinxin Shu
Hui Peng
Xing Wang

doi 10.3389/fphar.2025.1543575

ORIGINAL RESEARCH

Published on 03 Jan 2025

Modulation of gut microbiota, up-regulation of ZO-1, and promotion of metabolism as therapeutic mechanisms of indole-3-carbinol against obesity in mice

XuWen Mao
Guliruoyi Paerhati
Yuche Wu
Lu Feng Cheng

doi 10.3389/fphar.2024.1499142

438 views

ORIGINAL RESEARCH

Published on 11 Nov 2024

Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation

Gaetano Marverti
Maria Gaetana Moschella
Alice Belardo
Michele Lamesta
Giada Mercanile
Lorenzo Tagliazucchi
Daniele Aiello
Alberto Venturelli
Davide Illuminati
4 more
Domenico D’Arca

Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation

doi 10.3389/fphar.2024.1477318

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Experimental Pharmacology and Drug Discovery

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