Allergen cross-reactivity - a challenge in daily practice

Allergology frequently grapples with the increasing prevalence of cross-reactivity among diverse allergen families. This issue complicates clinical scenarios, presenting puzzling problems that can undermine the interpretation of diagnostic tests and the crafting of effective management strategies. This complexity is often exacerbated by a lack of comprehensive understanding regarding which allergens are likely to react with each other, leading to potential misdiagnosis and suboptimal patient care.

This Research Topic aims to elucidate the mechanisms of allergen cross-reactivity, improve diagnostic accuracy, and refine management plans for affected patients. By focusing on these aspects, the research seeks to clarify the underlying patterns and triggers of cross-reactivity, potentially revolutionizing the approach to allergy care and patient management.

To gather further insights into this multifaceted issue, we welcome original research articles, clinical trials, case studies, mini-reviews, reviews, viewpoints and perspectives covering, but not limited to, the following themes:

• Advances in molecular allergology for better prediction of cross-reactions
• Case studies detailing unusual cross-reactivity scenarios
• Impact of cross-reactivity on patient quality of life
• Novel therapeutic approaches for managing cross-reactivity
• Technological enhancements in allergen testing methodologies

Keywords: allergy, cross-reactivity, allergenic proteins, cross-reactive proteins, allergenic components, component-resolved diagnostics, non-specific lipid transfer proteins, PR-10, globulins

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.