About this Research Topic
The primary aim of this Research Topic is to present innovative research and comprehensive reviews on the potential of marine natural products to address global health challenges. This encompasses the discovery, synthesis, and application of bioactive compounds isolated from marine sources, highlighting their potential as high-quality pharmaceutical candidates. By focusing on such compounds, we aim to provide significant solutions to pressing health issues, including infectious and chronic inflammatory diseases, various cancers, the challenges of aging societies, and rising healthcare costs.
This Research Topic will cover a wide range of topics related to marine natural products, including but not limited to:
• Exploration and Discovery: Novel methodologies and technologies for the discovery of marine-derived compounds, including metagenomics, bioinformatics, and high-throughput screening.
• Chemical Diversity and Structural Elucidation: Structural characterization and elucidation of bioactive compounds isolated from marine organisms, including natural product chemistry and spectroscopic techniques.
• Biosynthesis and Metabolic Pathways: Insights into the biosynthesis and metabolic pathways of marine natural products, including genomic and transcriptomic analyses.
• Biological Activities and Pharmacological Potential: Evaluation of the biological activities and pharmacological properties of marine-derived compounds, including antimicrobial, anticancer, anti-inflammatory, and neuroprotective activities.
• Drug Development and Biotechnological Applications: Development of marine natural products as lead compounds for drug discovery, as well as their potential applications in biotechnology, agriculture, and environmental remediation.
Please Note:
1. Please self-assess your MS using the ConPhyMP tool (https://ga-online.org/best-practice/), and follow the standards established in the ConPhyMP statement Front. Pharmacol. 13:953205. All the manuscripts need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here). Importantly, please ascertain that the ethnopharmacological context is clearly described (pillar 3d) and that the material investigated is characterized in detail (pillars 2 a and b).
2. In silico studies like network analyses or docking studies are generally not accepted unless they are followed by an in vitro or in vivo analysis of the material under investigation.
3. In addition, for manuscripts dealing with plant extracts or other natural substances/compounds, the composition and the stability of the study material must be described in sufficient detail. In particular, for extracts, chromatograms with characterization of the dominating compound(s) are requested. The level of purity must be proven and included.
Keywords: Marine natural products, Synthetic compounds, microorganisms, chronic diseases, Inflammation, cancer, mechanisms
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.