About this Research Topic
The fight against cancer is undergoing a paradigm shift with the emergence of innovative strategies in Cancer Immunity & Immunotherapy. These approaches harness the body's own immune system to recognize and eliminate cancer cells. This field encompasses a diverse range of therapies, including checkpoint blockade, CAR T cell therapy, cytokine therapy, and more. One recent advancement is Bispecific T cell engagers (BiTEs), represent a powerful class of engineered antibodies that bridge immune cells to cancer cells for targeted destruction. Researchers are constantly exploring novel therapeutic strategies to improve effectiveness, overcome resistance, and personalize treatments for various cancers. Each approach offers unique advantages and holds immense promise for revolutionizing cancer treatment.
This Research Topic delves into the cutting-edge advancements within Cancer Immunity & Immunotherapy. We aim to showcase the latest developments across various immunotherapeutic approaches, explore their efficacy in diverse cancers, and identify strategies to overcome current limitations. Recent progress in areas like overcoming T cell exhaustion and managing cytokine release syndrome is paving the way for improved clinical outcomes. By fostering collaboration and knowledge sharing, we hope to accelerate the development and widespread application of these therapies, ushering in a new era of effective cancer treatment through Cancer Immunity & Immunotherapy.
This Research Topic welcomes a variety of article types, including Original Research, Reviews, Mini-Reviews, Methods papers, Case Reports, and Perspective pieces. We encourage submissions that explore, but are not limited to, the following themes within Cancer Immunity & Immunotherapy:
• Novel therapeutic strategies and mechanisms for enhanced immune response against various cancers.
• Preclinical and clinical development of immunotherapies for diverse cancer types, with a particular focus on solid tumors, a critical area of ongoing exploration.
• Understanding and overcoming resistance mechanisms to improve the efficacy of Cancer Immunity & Immunotherapy.
• Combination therapies utilizing multiple immunomodulatory agents to optimize the overall immune response.
• Addressing challenges associated with immunotherapy development and delivery to ensure wider patient accessibility.
• Clinical trial design and optimization for the advancement of Cancer Immunity & Immunotherapy.
• The ethical considerations and future directions for various immunotherapeutic approaches within the evolving field of Cancer Immunity & Immunotherapy.
Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by robust and relevant validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this topic.
This Research Topic delves into the cutting-edge advancements within Cancer Immunity & Immunotherapy. We aim to showcase the latest developments across various immunotherapeutic approaches, explore their efficacy in diverse cancers, and identify strategies to overcome current limitations. Recent progress in areas like overcoming T cell exhaustion and managing cytokine release syndrome is paving the way for improved clinical outcomes. By fostering collaboration and knowledge sharing, we hope to accelerate the development and widespread application of these therapies, ushering in a new era of effective cancer treatment through Cancer Immunity & Immunotherapy.
This Research Topic welcomes a variety of article types, including Original Research, Reviews, Mini-Reviews, Methods papers, Case Reports, and Perspective pieces. We encourage submissions that explore, but are not limited to, the following themes within Cancer Immunity & Immunotherapy:
• Novel therapeutic strategies and mechanisms for enhanced immune response against various cancers.
• Preclinical and clinical development of immunotherapies for diverse cancer types, with a particular focus on solid tumors, a critical area of ongoing exploration.
• Understanding and overcoming resistance mechanisms to improve the efficacy of Cancer Immunity & Immunotherapy.
• Combination therapies utilizing multiple immunomodulatory agents to optimize the overall immune response.
• Addressing challenges associated with immunotherapy development and delivery to ensure wider patient accessibility.
• Clinical trial design and optimization for the advancement of Cancer Immunity & Immunotherapy.
• The ethical considerations and future directions for various immunotherapeutic approaches within the evolving field of Cancer Immunity & Immunotherapy.
Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by robust and relevant validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this topic.
Keywords: Cancer Immunity & Immunotherapy, T cell therapy, Checkpoint blockade, Immunotherapy resistance, Combination immunotherapy, Solid tumors, CAR T cell therapy, BiTEs, Cytokine therapy, Cancer vaccine, Immune checkpoint inhibitors
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
