Antibiotic resistance in gastrointestinal infections has become a significant concern in recent years. Gastrointestinal infections, caused by various pathogens such as Salmonella, Escherichia coli, and Campylobacter, are widespread and can lead to severe illness. However, the overuse and misuse of antibiotics in both clinical and agricultural settings have contributed to the emergence of antibiotic-resistant strains of these bacteria. This resistance can limit the effectiveness of commonly used antibiotics, making the treatment of gastrointestinal infections more challenging. Furthermore, the spread of antibiotic-resistant bacteria through food, water, and person-to-person transmission has heightened the risk of treatment failure and increased the potential for outbreaks. Antibiotic resistance not only limits the effectiveness of traditional treatment options but also increases the risk of treatment failure and disease complications. Therefore, understanding the mechanisms of antibiotic resistance in gastrointestinal Infections, identifying the specific pathogens involved, and developing alternative strategies for treatment and prevention are crucial to effectively combat this growing healthcare challenge.
The article collection will explore the challenges and advances in diagnosing antibiotic-resistant infections accurately and create tools to fight this challenge. It will evaluate the effectiveness of current diagnostic methods and explore novel approaches for early identification and surveillance. Furthermore, the research topic will focus on investigating innovative strategies for the treatment of antibiotic-resistant infections, including the development of new antimicrobial agents and the implementation of infection control measures and the use of in silico tools on the discovery of new potential antibiotics. Understanding the intricate dynamics of antibiotic resistance infections and exploring effective diagnostic and treatment strategies is crucial for combating this global healthcare issue and ensuring patient safety.
• Research on isolation, identification, and characterization of strains causing gastrointestinal diseases with a multiresistant profile.
• Identification and characterization of mechanisms of resistance
• No-drugs alternatives for the treatment of multiresistant infections (i.e. probiotics, natural compounds, bacteriophages …)
• In silico discovery of new antimicrobial drugs
• Pangenome characterization of multiresistant organisms
• Multiresistant organisms from both animals and humans.
Keywords:
Gastrointestinal infections, Multidrug resistant bacteria, Antibiotics, in silico, Human gastrointestinal infections, Animal gastrointestinal infections
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Antibiotic resistance in gastrointestinal infections has become a significant concern in recent years. Gastrointestinal infections, caused by various pathogens such as Salmonella, Escherichia coli, and Campylobacter, are widespread and can lead to severe illness. However, the overuse and misuse of antibiotics in both clinical and agricultural settings have contributed to the emergence of antibiotic-resistant strains of these bacteria. This resistance can limit the effectiveness of commonly used antibiotics, making the treatment of gastrointestinal infections more challenging. Furthermore, the spread of antibiotic-resistant bacteria through food, water, and person-to-person transmission has heightened the risk of treatment failure and increased the potential for outbreaks. Antibiotic resistance not only limits the effectiveness of traditional treatment options but also increases the risk of treatment failure and disease complications. Therefore, understanding the mechanisms of antibiotic resistance in gastrointestinal Infections, identifying the specific pathogens involved, and developing alternative strategies for treatment and prevention are crucial to effectively combat this growing healthcare challenge.
The article collection will explore the challenges and advances in diagnosing antibiotic-resistant infections accurately and create tools to fight this challenge. It will evaluate the effectiveness of current diagnostic methods and explore novel approaches for early identification and surveillance. Furthermore, the research topic will focus on investigating innovative strategies for the treatment of antibiotic-resistant infections, including the development of new antimicrobial agents and the implementation of infection control measures and the use of in silico tools on the discovery of new potential antibiotics. Understanding the intricate dynamics of antibiotic resistance infections and exploring effective diagnostic and treatment strategies is crucial for combating this global healthcare issue and ensuring patient safety.
• Research on isolation, identification, and characterization of strains causing gastrointestinal diseases with a multiresistant profile.
• Identification and characterization of mechanisms of resistance
• No-drugs alternatives for the treatment of multiresistant infections (i.e. probiotics, natural compounds, bacteriophages …)
• In silico discovery of new antimicrobial drugs
• Pangenome characterization of multiresistant organisms
• Multiresistant organisms from both animals and humans.
Keywords:
Gastrointestinal infections, Multidrug resistant bacteria, Antibiotics, in silico, Human gastrointestinal infections, Animal gastrointestinal infections
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.