About this Research Topic
Radiolabeled biologics whether amino acids, cells, antibodies, proteins, viruses or synthetic ligands have potential for functional imaging and therapy. To date, one of the promising molecular imaging tools positron emission tomography (PET) has been used to diagnose and monitor the progression of diseases. For example, PET radioligands are helpful in detecting acute neuroinflammation which plays an important role in immune-mediated disorders such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS) and depression, as well as chronic neuroinflammation which is associated with profound axonal damage and neuronal cell death, and contributes to mild cognitive impairment (MCI); dementia syndromes (loss of cognitive functions); several neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD); and psychiatric disorders.
Understanding the complexity of biological processes in various brain diseases including ischemic brain stroke, brain tumors etc. is a major challenge. This goal of this research topic describes state- of-the-art PET-based imaging and multimodal imaging utilizing functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), and other advanced neuroimaging to study various degenerative diseases and highlights the key advancements in this field.
The scope in research refers to the development of radiopharmaceuticals, their targeted delivery to brain for the diagnosis and treatment of neuroinflammation and neurodegenerative diseases. We are interested in the manuscripts identifying the potential of various radionuclide imaging with promising potential in the diagnosis of various neuroinflammatory and brain disorders.
Understanding the complexity of biological processes in various brain diseases including ischemic brain stroke, brain tumors etc. is a major challenge. This goal of this research topic describes state- of-the-art PET-based imaging and multimodal imaging utilizing functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), and other advanced neuroimaging to study various degenerative diseases and highlights the key advancements in this field.
The scope in research refers to the development of radiopharmaceuticals, their targeted delivery to brain for the diagnosis and treatment of neuroinflammation and neurodegenerative diseases. We are interested in the manuscripts identifying the potential of various radionuclide imaging with promising potential in the diagnosis of various neuroinflammatory and brain disorders.
Keywords: Positron Emission Tomography (PET), Neuroinflammation, Neurodegenerative diseases, Biomarkers, Radiotracer, Receptors.
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