About this Research Topic
This Research Topic is part of a series with:
Natural Products and Their Synthetic Scaffolds for Chronic Diseases: A Ray of Hope
For decades, natural products, from both terrestrial and marine sources, have been a significant source of therapeutic remedies. Pharmaceutical companies still primarily consider the use of nature-derived, bioactive substances in the development of new drugs and traditional medicine. More than 80% to 85% of people throughout the world rely on traditional medicine (TM), as their primary form of healthcare. The easily available TM, mostly herbal products prepared from whole herbs or their extracts, have a significant economic role in many Asian, African, American, and European nations. Therefore, it has become urgent to increase the constituents' quality, safety, and effectiveness of TM. This can only be accomplished by scientifically validating the lead compounds in TM's chemical foundation and their mode of action. Thanks to advanced technologies and equipment it now has made it easy to create the scaffolds of natural products in the lab, saving a great deal of time as compared to isolating the natural product from its source.
The goal of scientifically validating traditional medicines (TM) and their synthetic analogs is to produce high-quality pharmaceutical products. These products have the potential to provide significant solutions to a range of global health challenges. These challenges include infectious diseases, chronic inflammatory conditions, various forms of cancer, the healthcare demands of aging populations, and the escalating costs of healthcare. This Research Topic invites original research and review articles on the isolation of bioactive molecules from terrestrial and marine sources of natural products or their synthetic scaffolds. Emphasis is placed on describing the full range of scientific studies, including isolation, synthesis and structure elucidation, bioactivity screening of compounds, and identification of drug lead compounds such as antimicrobials, anti-inflammatory, anti-diabetic and anti-cancers.
This Research Topic is intended to cover scientific and experimental data, as well as information on natural or synthetic compounds, related to the following:
• Evaluating the potential of secondary metabolites against chronic diseases through in vitro, in vivo, or in-silico assays.
• Elucidation of the mechanisms of these medicinal compounds and the fundamental processes by which products derived from terrestrial and marine sources function or act.
• Investigation of natural products exhibiting efficient bioactivity.
• Exploration of synthetic compounds demonstrating potential bioactivity.
• Application of biomolecules, either derived from natural terrestrial and marine sources or synthesized, in experimental or clinical studies.
Natural Products and Their Synthetic Scaffolds for Chronic Diseases: A Ray of Hope
For decades, natural products, from both terrestrial and marine sources, have been a significant source of therapeutic remedies. Pharmaceutical companies still primarily consider the use of nature-derived, bioactive substances in the development of new drugs and traditional medicine. More than 80% to 85% of people throughout the world rely on traditional medicine (TM), as their primary form of healthcare. The easily available TM, mostly herbal products prepared from whole herbs or their extracts, have a significant economic role in many Asian, African, American, and European nations. Therefore, it has become urgent to increase the constituents' quality, safety, and effectiveness of TM. This can only be accomplished by scientifically validating the lead compounds in TM's chemical foundation and their mode of action. Thanks to advanced technologies and equipment it now has made it easy to create the scaffolds of natural products in the lab, saving a great deal of time as compared to isolating the natural product from its source.
The goal of scientifically validating traditional medicines (TM) and their synthetic analogs is to produce high-quality pharmaceutical products. These products have the potential to provide significant solutions to a range of global health challenges. These challenges include infectious diseases, chronic inflammatory conditions, various forms of cancer, the healthcare demands of aging populations, and the escalating costs of healthcare. This Research Topic invites original research and review articles on the isolation of bioactive molecules from terrestrial and marine sources of natural products or their synthetic scaffolds. Emphasis is placed on describing the full range of scientific studies, including isolation, synthesis and structure elucidation, bioactivity screening of compounds, and identification of drug lead compounds such as antimicrobials, anti-inflammatory, anti-diabetic and anti-cancers.
This Research Topic is intended to cover scientific and experimental data, as well as information on natural or synthetic compounds, related to the following:
• Evaluating the potential of secondary metabolites against chronic diseases through in vitro, in vivo, or in-silico assays.
• Elucidation of the mechanisms of these medicinal compounds and the fundamental processes by which products derived from terrestrial and marine sources function or act.
• Investigation of natural products exhibiting efficient bioactivity.
• Exploration of synthetic compounds demonstrating potential bioactivity.
• Application of biomolecules, either derived from natural terrestrial and marine sources or synthesized, in experimental or clinical studies.
Keywords: Synthetic compounds, Structure elucidation, chronic diseases, Inflammation, cancer, mechanisms, Terrestrial and marine natural compounds
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