Frontiers | Decoding the Epigenetic Landscape: Elucidating Cancer Pathology and Identifying Novel Therapeutic Targets

Decoding the Epigenetic Landscape: Elucidating Cancer Pathology and Identifying Novel Therapeutic Targets

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ORIGINAL RESEARCH

Published on 19 Feb 2025

Integration of multi-omics profiling reveals an epigenetic-based molecular classification of lung adenocarcinoma: implications for drug sensitivity and immunotherapy response prediction

Ning Wang
Yinan Li
Yaoyao Wang
Wenting Wang

doi 10.3389/fphar.2025.1540477

120 views

ORIGINAL RESEARCH

Published on 18 Feb 2025

Exploring the role of epigenetic regulation in cancer prognosis with epigenetic score

Ruiguang Zhang
Shimin Jin
Qi Xu
Rongxiao Dai

doi 10.3389/fphar.2025.1538205

214 views

ORIGINAL RESEARCH

Published on 14 Feb 2025

Identification of potential diagnostic targets and therapeutic strategies for anoikis-related biomarkers in lung squamous cell carcinoma using machine learning and computational virtual screening

Xin Zhang
Jing Zou
Jinghua Ning
Yanhong Zhao
Run Qu
Yuzhe Zhang

doi 10.3389/fphar.2025.1500968

250 views

ORIGINAL RESEARCH

Published on 29 Jan 2025

NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells

Jianfen Shen
Shuo Zhang
Yan Song
Leiming Yang
Qi Huang
Pengyu Wang
Youzhi Zhang

doi 10.3389/fphar.2024.1531220

251 views

ORIGINAL RESEARCH

Published on 22 Jan 2025

Development and pan-cancer validation of an epigenetics-based random survival forest model for prognosis prediction and drug response in OS

Chaoyi Yin
Kede Chi
Zhiqing Chen
Shabin Zhuang
Yongsheng Ye
Binshan Zhang
Cailiang Cai

doi 10.3389/fphar.2025.1529525

328 views

ORIGINAL RESEARCH

Published on 15 Jan 2025

Intratumor microbiome-derived butyrate promotes chemo-resistance in colorectal cancer

Linsheng Xu
Bingde Hu
Jingli He
Xin Fu
Na Liu

doi 10.3389/fphar.2024.1510851

504 views
1 citation

ORIGINAL RESEARCH

Published on 14 Jan 2025

DNA methylation inhibitors adverse reaction characteristic analysis: an analysis based on the European spontaneous adverse event reporting system

Xia Zhang
Yuyu Liu
Qingwang Hou
Yongxin Guo
Youfu He

doi 10.3389/fphar.2024.1527903

322 views

ORIGINAL RESEARCH

Published on 13 Jan 2025

Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma

Jingyuan Wang
Shuai Yan

doi 10.3389/fphar.2024.1523779

421 views

ORIGINAL RESEARCH

Published on 21 Nov 2024

The role of epigenetic regulation in pancreatic ductal adenocarcinoma progression and drug response: an integrative genomic and pharmacological prognostic prediction model

Kang Fu
Junzhe Su
Yiming Zhou
Xiaotong Chen
Xiao Hu

doi 10.3389/fphar.2024.1498031

932 views

ORIGINAL RESEARCH

Published on 08 Nov 2024

Prognostic characteristics and drug sensitivity analysis of hepatocellular carcinoma based on histone modification-related genes: a multi-omics integrated study revealing potential therapeutic targets and individualized treatment strategies

Ping Sun
Zheng Ding
Juan Chen
Kezhen Ou
Dianjie Zhou
Rui Li
Tianxiang Gu
He Sun
Ying Cheng

doi 10.3389/fphar.2024.1489469

567 views

ORIGINAL RESEARCH

Published on 07 Nov 2024

A real-world study of adverse drug reactions of two isocitrate dehydrogenase inhibitor based on the US FDA adverse event reporting system and VigiAccess databases

Mengmeng Peng
Qian Guo
Zihan Dang
Baiquan Zhang
Manjuan Li
Zixuan Wang
Xuemian Lu
Jie Lin

doi 10.3389/fphar.2024.1489045

739 views

ORIGINAL RESEARCH

Published on 18 Oct 2024

Identification and validation of matrix metalloproteinase hub genes as potential biomarkers for Skin Cutaneous Melanoma

Zhongyi Zhang
Mei Zhao
Zubing Zhou
Xiaodan Ren
Yunliang He
Tao Shen
Hongping Zeng

doi 10.3389/fonc.2024.1471267

760 views
1 citation

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Articles

Integration of multi-omics profiling reveals an epigenetic-based molecular classification of lung adenocarcinoma: implications for drug sensitivity and immunotherapy response prediction

Exploring the role of epigenetic regulation in cancer prognosis with epigenetic score

Identification of potential diagnostic targets and therapeutic strategies for anoikis-related biomarkers in lung squamous cell carcinoma using machine learning and computational virtual screening

NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells

Development and pan-cancer validation of an epigenetics-based random survival forest model for prognosis prediction and drug response in OS

Intratumor microbiome-derived butyrate promotes chemo-resistance in colorectal cancer

DNA methylation inhibitors adverse reaction characteristic analysis: an analysis based on the European spontaneous adverse event reporting system

Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma

The role of epigenetic regulation in pancreatic ductal adenocarcinoma progression and drug response: an integrative genomic and pharmacological prognostic prediction model

Prognostic characteristics and drug sensitivity analysis of hepatocellular carcinoma based on histone modification-related genes: a multi-omics integrated study revealing potential therapeutic targets and individualized treatment strategies

A real-world study of adverse drug reactions of two isocitrate dehydrogenase inhibitor based on the US FDA adverse event reporting system and VigiAccess databases

Identification and validation of matrix metalloproteinase hub genes as potential biomarkers for Skin Cutaneous Melanoma

Frontiers in Pharmacology

Participating Journals

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