About this Research Topic
Fibrosis is a permanent scar tissue caused by the healing of wounds. The main pathological changes are increased fibrous connective tissue and decreased parenchymal cells. If the progress continues, it can lead to structural organ damage, functional decline, and even failure, seriously threatening human health and life. Tissue fibrosis is the leading cause of disability and death from many diseases worldwide. In particular, fibrosis can occur in the viscera, typically due to inflammation or damage. Therefore, fibrosis plays an essential role in the occurrence and development of significant organ diseases in the human body.
Following the previous topic: https://www.frontiersin.org/research-topics/35016/fibrotic-diseases-in-thorax-and-abdomainal-viscera-volume-ii/magazine, this research topic aims to explore the pathogenesis and pathophysiological process of fibrotic diseases in lungs, liver, brain, kidneys, bones, skin, eyes, prostate, and heart., as well as clinical case diagnosis and treatment research, including genome-wide screening of disease-related functional genes, pathogenesis, screening of susceptible populations, early diagnosis, pathological analysis, screening of therapeutic targets, and new drugs development and related research.
In this research topic, we welcome original research articles and reviews, including but not limited to the following themes:
• Nature, etiology and pathophysiology of fibrotic disorders
• Biologically relevant aspects of the epidemiology, diagnosis, and treatment
• Drug discovery and development
• Basic and Clinical Pharmacology
Following the previous topic: https://www.frontiersin.org/research-topics/35016/fibrotic-diseases-in-thorax-and-abdomainal-viscera-volume-ii/magazine, this research topic aims to explore the pathogenesis and pathophysiological process of fibrotic diseases in lungs, liver, brain, kidneys, bones, skin, eyes, prostate, and heart., as well as clinical case diagnosis and treatment research, including genome-wide screening of disease-related functional genes, pathogenesis, screening of susceptible populations, early diagnosis, pathological analysis, screening of therapeutic targets, and new drugs development and related research.
In this research topic, we welcome original research articles and reviews, including but not limited to the following themes:
• Nature, etiology and pathophysiology of fibrotic disorders
• Biologically relevant aspects of the epidemiology, diagnosis, and treatment
• Drug discovery and development
• Basic and Clinical Pharmacology
Keywords: Fibrosis, Pathogenesis, Organ Damage, Therapeutic Targets, Drug Development
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
