About this Research Topic
This Research Topic is the second volume of the Research Topic "Exercise-Induced Neuroplasticity in Neurodegeneration Diseases". Please see the first volume here.
Neurodegenerative diseases are disabling and fatal neurological disorders affecting millions of people worldwide. With the continuous growth of the aging population, the incidence of neurodegenerative diseases is projected to more than double by 2050. Despite extensive efforts from researchers globally, effective treatments for combating these diseases remain limited, with most treatments offering only transient benefits. Exercise, as a low-cost, low-risk, and scalable non-pharmaceutical intervention, has garnered increasing attention for its potential role in ameliorating cognitive impairment. A growing body of epidemiological evidence supports the notion that exercise is beneficial for preventing brain aging and maintaining brain function. While neuroplasticity has been implicated in exercise-related cognitive improvements, the underlying mechanisms remain incompletely understood. This gap in understanding highlights the need for further investigation into how exercise influences neuroplasticity and cognitive function in the context of neurodegenerative diseases.
This research topic aims to explore the benefits of exercise on cognitive impairment and to investigate the mechanisms underlying these beneficial effects at various levels of the brain and nervous system. By examining the interplay between exercise and neuroplasticity, this research seeks to uncover specific pathways and processes that contribute to cognitive improvements in individuals with neurodegenerative diseases. The research will address key questions such as: What are the specific neural mechanisms through which exercise exerts its effects? How do these mechanisms vary across different neurodegenerative conditions? What role does exercise play in modulating brain networks and functional connectivity?
To gather further insights into the complex relationship between exercise and neuroplasticity in neurodegenerative diseases, we welcome articles addressing, but not limited to, the following themes:
- Mechanisms of exercise on neuroplasticity and metaplasticity.
- Neural mechanisms of exercise on neurodegenerative diseases.
- Mechanisms of brain functional change due to exercise, particularly at the brain network level.
- Research on assessment methods for neurodegenerative diseases.
- Physical activity strategies or exercise programs for neurodegenerative diseases.
Neurodegenerative diseases are disabling and fatal neurological disorders affecting millions of people worldwide. With the continuous growth of the aging population, the incidence of neurodegenerative diseases is projected to more than double by 2050. Despite extensive efforts from researchers globally, effective treatments for combating these diseases remain limited, with most treatments offering only transient benefits. Exercise, as a low-cost, low-risk, and scalable non-pharmaceutical intervention, has garnered increasing attention for its potential role in ameliorating cognitive impairment. A growing body of epidemiological evidence supports the notion that exercise is beneficial for preventing brain aging and maintaining brain function. While neuroplasticity has been implicated in exercise-related cognitive improvements, the underlying mechanisms remain incompletely understood. This gap in understanding highlights the need for further investigation into how exercise influences neuroplasticity and cognitive function in the context of neurodegenerative diseases.
This research topic aims to explore the benefits of exercise on cognitive impairment and to investigate the mechanisms underlying these beneficial effects at various levels of the brain and nervous system. By examining the interplay between exercise and neuroplasticity, this research seeks to uncover specific pathways and processes that contribute to cognitive improvements in individuals with neurodegenerative diseases. The research will address key questions such as: What are the specific neural mechanisms through which exercise exerts its effects? How do these mechanisms vary across different neurodegenerative conditions? What role does exercise play in modulating brain networks and functional connectivity?
To gather further insights into the complex relationship between exercise and neuroplasticity in neurodegenerative diseases, we welcome articles addressing, but not limited to, the following themes:
- Mechanisms of exercise on neuroplasticity and metaplasticity.
- Neural mechanisms of exercise on neurodegenerative diseases.
- Mechanisms of brain functional change due to exercise, particularly at the brain network level.
- Research on assessment methods for neurodegenerative diseases.
- Physical activity strategies or exercise programs for neurodegenerative diseases.
Keywords: exercise, physical activity, neuroplasticity, cognitive function
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
