About this Research Topic
The investigation of cellular survival strategies holds substantial importance across various aspects, including biosynthesis, signaling, inflammation, and metabolism. This recognition has motivated major efforts to elucidate the underlying mechanisms involved in sensing stress and damage and initiating protective responses in normal cells as well as their roles in disease contexts. There is significant interest in comprehending the underlying molecular and cellular mechanisms in coping with stress and damage, as well as the interplay among cellular signaling pathways and processes, with the goal of bringing insights into a wide range of biological phenomena and systems.
The scope of this Research Topic is to provide a set of advanced research that addresses significant gaps in our understanding of the molecular and cellular mechanisms underlying cell survival strategies and their pathological implications. This includes the mechanisms involved in safeguarding organellar integrity, restructuring cell signaling and processes, as well as, stress granule-mediated protection, all vital for cell survival. We encourage contributions covering a wide range of topics, including but not limited to the following:
• Cellular responses to organellar damage
• Remodelling of cell signaling and processes during stress and damage
• Stress granule formation and function
• Inter-organelle interaction and organization for cell survival
We accept different article types including Mini-Reviews, Brief Research Reports and Perspectives. A full list of accepted article types, including descriptions, can be found at this link.
Keywords: stress response, organellar damage, mTOR, AMPK, autophagy, stress granule, stress survival
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.