About this Research Topic
There have been several reports on oral-gut microbiome transmission and its effects on host health. The oral microbiome and its metabolome are associated with oral health, and they are also associated with systemic health via the oral-gut axis. Assessment of oral and gut microbial communities has become prevalent in clinical studies as therapeutics targeting the microbiome are increasingly. Methods used during the workflow while generating microbial genetic sequencing data can vary widely between studies, including sample collection method, storage, and DNA extraction, which can all influence observed microbial composition. The role of the oral microbiome in systemic disease, especially gastrointestinal disease, can be explained by the oral-gut axis. The oral microbiome and its metabolites may translocate to the gastrointestinal tract, inducing dysbiosis and intestinal inflammation. Despite their importance, there is limited knowledge of the oral microbiome and metabolome of humans.
This research topic aims to investigate the interconnectedness between the oral microbiome and the gut microbiome. While considerable attention has been given to understanding these microbiomes independently, there's a growing recognition of the extensive bidirectional relationship between these two systems. By investigating and unravelling the intricate link between the oral and gut microbiomes, we hope this research exploitation can inform effective therapeutic strategies and fuel comprehensive health care discussions and practices. This topic will contribute significantly to the body of knowledge surrounding oral health, gut health, and the interplay between the two. Example of thematics related to the oral-gut axis to be further investigated in this Research Topic are: the relationship between oral and gut microbiota in alcohol dependence (AD), in diabetes, in inflammatory bowel disease…, the importance of dental health (affected by many factors, including the oral microbiome and metabolome profiles) and dental care for longevity and health, the characterization of the oral microbiome and gut microbiome of periodontal diseases or dental caries, the impact of processing and storage methods on oral and gut microbiome composition, and also the intervening measure to maintain oral/gut health by influencing gut/oral microbiome.
In this Research Topic we welcome original research, review, mini-review, perspective, hypothesis & theory, methods, opinion and systematic review articles contributing to a comprehensive understanding of this dynamic interplay on themes including, but not limited to:
1. Oral-Gut Microbiome Axis: An Overview - Providing an in-depth review of existing knowledge regarding key interactions and communication between oral and gut microbiomes.
2. Microbial Migration: From Oral to Gut - Chromatographic analyses demonstrate the dynamic movements of microbiota from oral to gut, transforming and adapting to their new environments.
3. Impact on Health and Disease - Delving into the role of oral and gut microbiome interactions in susceptibility to and development of various health conditions such as inflammatory bowel diseases, obesity, cancer, cardiovascular diseases, and neurological disorders.
4. Influence of Diet on the Oral-Gut Microbiota Link - Exploring how nutritional habits could mediate the oral-gut microbiota axis impacting health and disease.
5. Therapeutic Implications and Interventions - Considering potential strategies to manipulate and optimize the oral and gut microbiome for better health outcomes.
Topic Editor Zhangran Chen is now employed by Shenzhen Wedge Microbiology Research Co. Ltd. All other topic editors declare no competing interests with regard to the Research Topic subject.
This research topic aims to investigate the interconnectedness between the oral microbiome and the gut microbiome. While considerable attention has been given to understanding these microbiomes independently, there's a growing recognition of the extensive bidirectional relationship between these two systems. By investigating and unravelling the intricate link between the oral and gut microbiomes, we hope this research exploitation can inform effective therapeutic strategies and fuel comprehensive health care discussions and practices. This topic will contribute significantly to the body of knowledge surrounding oral health, gut health, and the interplay between the two. Example of thematics related to the oral-gut axis to be further investigated in this Research Topic are: the relationship between oral and gut microbiota in alcohol dependence (AD), in diabetes, in inflammatory bowel disease…, the importance of dental health (affected by many factors, including the oral microbiome and metabolome profiles) and dental care for longevity and health, the characterization of the oral microbiome and gut microbiome of periodontal diseases or dental caries, the impact of processing and storage methods on oral and gut microbiome composition, and also the intervening measure to maintain oral/gut health by influencing gut/oral microbiome.
In this Research Topic we welcome original research, review, mini-review, perspective, hypothesis & theory, methods, opinion and systematic review articles contributing to a comprehensive understanding of this dynamic interplay on themes including, but not limited to:
1. Oral-Gut Microbiome Axis: An Overview - Providing an in-depth review of existing knowledge regarding key interactions and communication between oral and gut microbiomes.
2. Microbial Migration: From Oral to Gut - Chromatographic analyses demonstrate the dynamic movements of microbiota from oral to gut, transforming and adapting to their new environments.
3. Impact on Health and Disease - Delving into the role of oral and gut microbiome interactions in susceptibility to and development of various health conditions such as inflammatory bowel diseases, obesity, cancer, cardiovascular diseases, and neurological disorders.
4. Influence of Diet on the Oral-Gut Microbiota Link - Exploring how nutritional habits could mediate the oral-gut microbiota axis impacting health and disease.
5. Therapeutic Implications and Interventions - Considering potential strategies to manipulate and optimize the oral and gut microbiome for better health outcomes.
Topic Editor Zhangran Chen is now employed by Shenzhen Wedge Microbiology Research Co. Ltd. All other topic editors declare no competing interests with regard to the Research Topic subject.
Keywords: Oral Microbiome, Gut Microbiome, Oral-Gut Axis, Oral Health
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