About this Research Topic
Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide and regardless of intensive treatments, the prevalence of DKD remains high. Hyperglycemia is the primary etiological factor responsible for the development of diabetic kidney disease. Once hyperglycemia becomes established, multiple pathophysiological disturbances contribute to the onset and progression of diabetic kidney disease.
As part of the journal’s mission to address key subjects related to the challenging complications of Diabetes Mellitus, Frontiers in Clinical Diabetes and Healthcare is organizing a Research Topic focused on the 'Pathophysiology of Diabetic Kidney Disease'. Led by an expert team of specialists, the Research Topic will accept manuscripts within this area of research, with the aim of giving the reader an overview of the latest discoveries and new findings, analysis of previously published data, new opinions and perspectives, and methods and protocols (when relevant). For that reason, all article types accepted by Frontiers are encouraged.
Sub-themes for this Research Topic may include, but are not limited to:
- Hemodynamic factors relating to the pathophysiology of DKD
- Metabolic factors relating to the pathophysiology of DKD
- Signaling pathways involved in the onset and development of DKD
- The role of oxidative stress in the pathophysiology of DKD
- The role of autophagy in the pathophysiology of DKD
- The role of epigenetics in the pathophysiology of DKD
- The role of inflammation in the pathophysiology of DKD
- The role of fibrosis in the pathophysiology of DKD
- Renoprotective effects of antidiabetics beyond glucose control
As part of the journal’s mission to address key subjects related to the challenging complications of Diabetes Mellitus, Frontiers in Clinical Diabetes and Healthcare is organizing a Research Topic focused on the 'Pathophysiology of Diabetic Kidney Disease'. Led by an expert team of specialists, the Research Topic will accept manuscripts within this area of research, with the aim of giving the reader an overview of the latest discoveries and new findings, analysis of previously published data, new opinions and perspectives, and methods and protocols (when relevant). For that reason, all article types accepted by Frontiers are encouraged.
Sub-themes for this Research Topic may include, but are not limited to:
- Hemodynamic factors relating to the pathophysiology of DKD
- Metabolic factors relating to the pathophysiology of DKD
- Signaling pathways involved in the onset and development of DKD
- The role of oxidative stress in the pathophysiology of DKD
- The role of autophagy in the pathophysiology of DKD
- The role of epigenetics in the pathophysiology of DKD
- The role of inflammation in the pathophysiology of DKD
- The role of fibrosis in the pathophysiology of DKD
- Renoprotective effects of antidiabetics beyond glucose control
Keywords: diabetic kidney disease, DKD, pathophysiology, hemodynamic, metabolic, signal pathways, oxidative stress, autophagy, epigenetics, inflammation, fibrosis, antidiabetics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
