Methods of Tumor Diagnosis and Pivotal Gene Regulatory Mechanisms in Tumorigenesis and Development

With the advancement in tumor molecular biology and genomics, our understanding of tumor molecular phenotypes is constantly deepening. The strategy for tumor treatment has gradually shifted from a systemic chemotherapy stage, centered around the site and morphology of the disease, to an era of precision-targeted therapy targeting gene mutations. Tumor-targeted therapy refers to the method of treating tumors by specifically targeting molecules or signaling pathways that play an essential role in tumor occurrence and progression. Targeted therapy based on tumor-specific molecular phenotypes has become the preferred option for treating advanced tumors.

In-depth exploration of novel methods for the molecular diagnosis of tumors involves identifying key coding or non-coding genes, proteins, etc., in the development and progression of different tumors. We aim to study their molecular mechanisms in tumor development and their impact on the overall tumor microenvironment, tumor immunity, among other aspects.

This Research Topic seeks to provide current insights into the molecular mechanisms involved in tumor development and their influence on the broader tumor microenvironment, including aspects such as tumor immunity. Original Research articles and Reviews and Case Report are welcome, including but not limited to the following contents:

• Diagnostic methods for tumors
• Screening of tumor molecular markers
• Key differential genes involved in tumor development, such as MicroRNA, LnRNA, CircleRNA, and their effects on tumors
• The relationship between the tumor microenvironment and tumor immunity on Tumorigenesis
• Molecular Mechanisms of Key Proteins and Signal Pathways during Tumor Development"