About this Research Topic
Aging entails a gradual decline in cellular, tissue, and organ vitality and function, governed by intricate biological processes like cell apoptosis, DNA damage repair, and metabolic dysregulation. It correlates closely with various age-related diseases such as cardiovascular diseases, diabetes, and Alzheimer's disease. To effectively prevent and treat these ailments, in-depth research into the molecular mechanisms of aging is imperative. This understanding paves the way for innovative treatment modalities including gene editing, stem cell therapy, targeted drug development, advanced biomaterials, and the application of artificial intelligence and big data analytics.
Aging represents a multifaceted biological phenomenon encompassing systemic and multi-level changes in bodily functions and structures over time. Investigating aging sheds light on its biological mechanisms across cellular, tissue, and organ levels, encompassing alterations in gene expression, protein metabolism, and cellular signaling pathways. This elucidation aids in comprehending the impact of aging on physical health and disease development. Furthermore, aging research facilitates the identification of risk factors for various diseases associated with aging, fostering the development of enhanced preventive measures and intervention strategies. Understanding aging mechanisms also holds promise for extending lifespan through lifestyle modifications, dietary adjustments, and regular exercise, thereby enhancing quality of life and longevity.
This collection invites submissions including reviews and research articles related to, but not limited to, the following subthemes:
• Latest molecular mechanisms of aging-related diseases;
• Epigenetic studies related to aging;
• Stem cells and extracellular vesicles therapies in aging-related diseases;
• Advanced biomaterials therapies in aging-related diseases.
Aging represents a multifaceted biological phenomenon encompassing systemic and multi-level changes in bodily functions and structures over time. Investigating aging sheds light on its biological mechanisms across cellular, tissue, and organ levels, encompassing alterations in gene expression, protein metabolism, and cellular signaling pathways. This elucidation aids in comprehending the impact of aging on physical health and disease development. Furthermore, aging research facilitates the identification of risk factors for various diseases associated with aging, fostering the development of enhanced preventive measures and intervention strategies. Understanding aging mechanisms also holds promise for extending lifespan through lifestyle modifications, dietary adjustments, and regular exercise, thereby enhancing quality of life and longevity.
This collection invites submissions including reviews and research articles related to, but not limited to, the following subthemes:
• Latest molecular mechanisms of aging-related diseases;
• Epigenetic studies related to aging;
• Stem cells and extracellular vesicles therapies in aging-related diseases;
• Advanced biomaterials therapies in aging-related diseases.
Keywords: aging, biological mechanisms, age-related diseases, molecular research, therapeutic interventions
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
