About this Research Topic
The global prevalence of myopia is increasing dramatically, and by 2050, half of the world's population is estimated to be myopic. Especially axial high myopia poses a significant burden to clinicians. Myopia, especially high myopia, is a risk factor for glaucoma, and there is epidemiologic evidence that the risk of developing glaucoma is 2 to 3 times higher for myopic eyes and even higher in high myopic eyes. At the same time, myopic changes are similar to glaucomatous changes, which makes it difficult to distinguish between myopia and glaucoma, resulting in overdiagnosis and over-treatment. Established imaging technologies, such as OCT, which are the standard of care in glaucoma diagnostics, have little to no diagnostic reliability because of a higher rate of segmentation failures and lacking high myopic eyes in the normative database. Diagnosing and monitoring glaucoma progression in high myopic eyes, therefore, remains challenging and guidelines to address this challenge are needed.
The goal of this research topic is to address the challenges of glaucoma diagnostics in high myopic eyes. Diagnostic challenges can include clinical examination of high myopic eyes and the use of diagnostic tools such as OCT and OCT-Angiography (OCTA). Furthermore, this research topic is interested in the evaluation of already established OCT and OCTA parameters, including the following, but not limited to, parameters: The retinal nerve fibre layer (RNFL), Bruch's membrane opening (BMO) minimum rim width (MRW), ganglion cell inner plexiform layer (GCIPL), ganglion cell complex (GCC), superficial and deep capillary vessel density, choroidal thickness, and microvascular dropouts. Furthermore, the goal is to address new parameters and imaging techniques to characterize the myopic eye, including glaucomatous and non-glaucomatous changes. These new tools can be used to establish risk calculators for better glaucoma management in high myopic eyes.
We are interested in the following research subjects:
-Evaluation of established OCT parameters (GCIPL, GCC, BMO-MRW, RNFL and others)
-Evaluation of established OCTA parameters
-Clinical/photography-based features of high myopic eyes with and without glaucoma
-Development of new OCT and/or OCTA parameters to distinguish between myopia and glaucoma-related changes
-OCT-based parameters to characterize optic nerve head anatomy in non- and high myopes with and without glaucoma
-New techniques for high myopia and glaucoma management
We are interested in publishing original research, case report, review and mini-review type manuscripts. Other manuscript types will also be considered.
The goal of this research topic is to address the challenges of glaucoma diagnostics in high myopic eyes. Diagnostic challenges can include clinical examination of high myopic eyes and the use of diagnostic tools such as OCT and OCT-Angiography (OCTA). Furthermore, this research topic is interested in the evaluation of already established OCT and OCTA parameters, including the following, but not limited to, parameters: The retinal nerve fibre layer (RNFL), Bruch's membrane opening (BMO) minimum rim width (MRW), ganglion cell inner plexiform layer (GCIPL), ganglion cell complex (GCC), superficial and deep capillary vessel density, choroidal thickness, and microvascular dropouts. Furthermore, the goal is to address new parameters and imaging techniques to characterize the myopic eye, including glaucomatous and non-glaucomatous changes. These new tools can be used to establish risk calculators for better glaucoma management in high myopic eyes.
We are interested in the following research subjects:
-Evaluation of established OCT parameters (GCIPL, GCC, BMO-MRW, RNFL and others)
-Evaluation of established OCTA parameters
-Clinical/photography-based features of high myopic eyes with and without glaucoma
-Development of new OCT and/or OCTA parameters to distinguish between myopia and glaucoma-related changes
-OCT-based parameters to characterize optic nerve head anatomy in non- and high myopes with and without glaucoma
-New techniques for high myopia and glaucoma management
We are interested in publishing original research, case report, review and mini-review type manuscripts. Other manuscript types will also be considered.
Keywords: High myopia, Axial myopia, Glaucoma, OCT OCT-Angiography
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
