About this Research Topic
Cardiovascular disease (CVD) continues to be the leading cause of mortality worldwide, affecting individuals across all genders. Despite strides in understanding CVD, there remains a gap in fully addressing how sex differences influence responses to cardiovascular drugs, often leading to less effective treatment, particularly in women. Research increasingly suggests that biological differences impact the pathophysiology of CVD, resulting in varied drug responses that are not currently accounted for in standard guidelines.
This Research Topic aims to explore the mechanisms behind sex-specific responses to cardiovascular treatments, fostering an evidence base for more tailored approaches to therapy. By investigating these pharmacodynamic and pharmacokinetic differences, the goal is to contribute to a deeper understanding that may enhance clinical outcomes and inform future guidelines.
We welcome contributions in the following areas:
• Mechanisms of Sex-Specific Drug Responses: Studies on the molecular and physiological mechanisms underlying differential responses to cardiovascular drugs between men and women.
• Sex-Based Differences in CVD Pathophysiology: Research on how sex differences in disease progression affect pharmacological outcomes, highlighting implications for therapy.
• Personalized Treatment Models: Proposals for models and frameworks that support individualized treatment plans based on sex-specific responses to therapy.
• Novel Targets for Drug Development: Identification of new pharmacological targets with potential for sex-specific drug discovery in the cardiovascular field.
This Research Topic seeks to advance our knowledge of sex-specific pharmacology in cardiovascular care, encouraging contributions that may ultimately support more precise, patient-centered treatment strategies.
This Research Topic aims to explore the mechanisms behind sex-specific responses to cardiovascular treatments, fostering an evidence base for more tailored approaches to therapy. By investigating these pharmacodynamic and pharmacokinetic differences, the goal is to contribute to a deeper understanding that may enhance clinical outcomes and inform future guidelines.
We welcome contributions in the following areas:
• Mechanisms of Sex-Specific Drug Responses: Studies on the molecular and physiological mechanisms underlying differential responses to cardiovascular drugs between men and women.
• Sex-Based Differences in CVD Pathophysiology: Research on how sex differences in disease progression affect pharmacological outcomes, highlighting implications for therapy.
• Personalized Treatment Models: Proposals for models and frameworks that support individualized treatment plans based on sex-specific responses to therapy.
• Novel Targets for Drug Development: Identification of new pharmacological targets with potential for sex-specific drug discovery in the cardiovascular field.
This Research Topic seeks to advance our knowledge of sex-specific pharmacology in cardiovascular care, encouraging contributions that may ultimately support more precise, patient-centered treatment strategies.
Keywords: Hypertension, Pharmacology, Sex, Pharmacokinetics, Cardiovascular Drugs
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
