About this Research Topic
Magnetic resonance imaging (MRI) has become the state-of-the-art method for assessment of in vivo tissue composition and is currently the most reliable imaging modality for the evaluation of central nervous system, hepatic and pancreatic diseases. Proton magnetic resonance spectroscopy (1H-MRS) is now well-established as a state-of-the-art method for the quantification of tissue fat fraction and typification of fat, including in the liver and brown adipose tissues. 31P-MRS is also useful for the non-invasive study of mitochondrial function in vivo. Emerging methods using 13C or 2H-labelled tracers have been developed and offer promises to trace energy metabolism in vivo. Detection of these nuclei directly by spectroscopy or indirectly by chemical exchange saturation transfer (CEST) have been reported.
The overall goal of this special theme is to capture the breadth of nuclear magnetic resonance methods for the in vivo study of tissue-specific energy substrate metabolism in diabetes and other metabolic disorders.
Topics of interest include:
• Proton imaging for the quantification and characterization of tissue fat content
• 31P-MRS for the study of in vivo mitochondrial function
• Deuterium molecular imaging
• Hyperpolarized 13C-labelled tracers to quantify in vivo tissue metabolism
• Advances in MRI-based blood flow imaging
• Chemical exchange saturation transfer methods
The overall goal of this special theme is to capture the breadth of nuclear magnetic resonance methods for the in vivo study of tissue-specific energy substrate metabolism in diabetes and other metabolic disorders.
Topics of interest include:
• Proton imaging for the quantification and characterization of tissue fat content
• 31P-MRS for the study of in vivo mitochondrial function
• Deuterium molecular imaging
• Hyperpolarized 13C-labelled tracers to quantify in vivo tissue metabolism
• Advances in MRI-based blood flow imaging
• Chemical exchange saturation transfer methods
Keywords: Magnetic Resonance Spectroscopy, Imagining, in vivo, Metabolic Disorders, Adipose, Diabetes, Metobolism
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