About this Research Topic
The relationship between endocrine disorders and tumors has always been a hot topic in medical research. However, with a deeper understanding of the endocrine system, it has been found that nutritional metabolism also plays a crucial role in it. For example, glutamate dehydrogenase (GDH) is upregulated in colorectal cancer (CRC) cells and can induce epithelial-mesenchymal transition (EMT) to improve the proliferation and migration of CRC cells. In addition, Vitamin D receptor (VDR) has a significant impact on energy homeostasis through the modulation of RAS activity in the hypothalamus, while Vitamin D is closely related to obesity-related endocrine diseases.
The endocrine system is a complex system within the body that regulates various physiological processes, including cell growth and differentiation, through hormone signaling. Nutritional metabolism is the process by which cells acquire and utilize nutrients, which is closely related to the endocrine system. When these two systems become abnormal, tumor occurrence and development will be a potential outcome.
Studying why abnormalities in nutritional metabolism may lead to tumors and how they affect the occurrence and development of tumors may provide new ideas and approaches for the prevention and treatment of tumors. It includes the search for new therapeutic targets, the development of new drugs, and the optimization of existing treatments.
The focus of the Research Topic is to understand the relationship between changes in endocrine and nutritional metabolism and tumor development, as well as how to translate these findings into effective treatment strategies. Revealing the secret between endocrine and nutritional metabolic abnormalities and tumors, we look forward to sharing new discoveries and research results to provide more inspiration and motivation for future research.
This Research Topic is dedicated to the latest advances in the role of nutritional metabolic abnormalities in endocrine-related diseases and tumors. We encourage submissions of Original Research, Reviews, Mini-reviews, Methods, Perspectives, and Opinion articles. These submissions should focus on, but not be limited to, the following topics:
● Vitamin involvement in tumor development and progression
● Endocrine nutritional metabolic abnormalities between cancer and stromal cells in the tumor microenvironment
● New insights into nutritional metabolic abnormalities in endocrine-relate disease
● The impact of metabolism reprogramming on therapy responsiveness
● Endocrine-related deficiency associated with the risk of developing endocrine-related diseases and tumors
● Metabolism-targeted treatments and nutrients-based therapies
● The role of diets with different nutrient intakes on the outcomes of patients affected by endocrine-related tumors.
The endocrine system is a complex system within the body that regulates various physiological processes, including cell growth and differentiation, through hormone signaling. Nutritional metabolism is the process by which cells acquire and utilize nutrients, which is closely related to the endocrine system. When these two systems become abnormal, tumor occurrence and development will be a potential outcome.
Studying why abnormalities in nutritional metabolism may lead to tumors and how they affect the occurrence and development of tumors may provide new ideas and approaches for the prevention and treatment of tumors. It includes the search for new therapeutic targets, the development of new drugs, and the optimization of existing treatments.
The focus of the Research Topic is to understand the relationship between changes in endocrine and nutritional metabolism and tumor development, as well as how to translate these findings into effective treatment strategies. Revealing the secret between endocrine and nutritional metabolic abnormalities and tumors, we look forward to sharing new discoveries and research results to provide more inspiration and motivation for future research.
This Research Topic is dedicated to the latest advances in the role of nutritional metabolic abnormalities in endocrine-related diseases and tumors. We encourage submissions of Original Research, Reviews, Mini-reviews, Methods, Perspectives, and Opinion articles. These submissions should focus on, but not be limited to, the following topics:
● Vitamin involvement in tumor development and progression
● Endocrine nutritional metabolic abnormalities between cancer and stromal cells in the tumor microenvironment
● New insights into nutritional metabolic abnormalities in endocrine-relate disease
● The impact of metabolism reprogramming on therapy responsiveness
● Endocrine-related deficiency associated with the risk of developing endocrine-related diseases and tumors
● Metabolism-targeted treatments and nutrients-based therapies
● The role of diets with different nutrient intakes on the outcomes of patients affected by endocrine-related tumors.
Keywords: Tumor development and progression, Tumor metabolism, Hormone-related risk factors, Nutrition metabolism
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
