About this Research Topic
This Research Topic aims to explore the intricate relationship between stress, mental health, and the synapse. Stress, a prevalent factor in modern society, has been linked to numerous mental health conditions, such as anxiety disorders, depression, and neurodegenerative diseases. The synapse, a fundamental component of neural communication, plays a crucial role in mediating stress responses and shaping mental well-being. Understanding the underlying mechanisms and implications of stress-related synaptic alterations is imperative for advancing our knowledge in mental health research.
Goal:
The primary goal of this Research Topic is to delve into the complexities of stress-related synaptic changes and their impact on mental health. We aim to identify the mechanisms through which stress affects the structure and function of synapses, and explore the subsequent consequences on neuronal circuitry, cognition, and behavior, and how these may lead to or exacerbate mental health disorders. Furthermore, we seek to identify potential therapeutic targets and interventions that can mitigate the adverse effects of stress on mental health.
Scope and Information for Authors:
We welcome contributions from researchers and experts in the field to contribute original research articles, reviews, and perspectives related to stress, mental health, and the synapse. Specific themes to be addressed may include, but are not limited to:
- Molecular and cellular mechanisms underlying stress-induced synaptic alterations
- The role of synaptic plasticity in stress resilience and vulnerability
- Neurotransmitter systems involved in stress responses and mental health disorders
- The impact of stress on synaptic connectivity and circuitry
- Animal models of stress-related neuropathology with a focus on synaptic alterations
- Behavioral and cognitive consequences of stress-related synaptic changes
Furthermore, we encourage authors to explore potential therapeutic strategies that target synaptic modulation to ameliorate stress-related mental health disorders. The insights gained from this Research Topic will enhance our understanding of the intricate interplay between stress, mental health, and synaptic plasticity, ultimately leading to the development of novel and effective interventions in this critical area of research.
Keywords: Neurotransmitter, Neurotransmitter Receptor, stress, mental health, anxiety, depression, neurotransmitter transporter
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.