About this Research Topic
Despite the lack of a successful treatment for Duchenne muscular dystrophy (DMD), the pursuit continues to discover innovative therapies to enhance muscle function, improve the quality of life, and extend the lifespan of individuals affected by this debilitating condition.
Considering this critical issue, the overarching goal of this Research Topic was to collect innovative proposals, aimed at deepening our comprehension of the mechanisms underlying muscle degeneration and regeneration in DMD. Beyond advancing scientific understanding, our overarching objective is to foster collaboration among researchers, catalyzing the exchange of insights and expertise in the pursuit of accelerated, science-driven innovation in this field.
Advances in science and rehabilitation techniques provide support only for secondary problems, such as muscle weakness and respiratory failure, seeking to improve the quality of life and prolong the survival of these patients, the fundamental challenge of curing DMD persists.
Several studies underscore the significant direct and indirect costs associated with treatment, with expenses escalating as the disease progresses.
Planning for patients' healthcare must factor in the expenses for the health system, underscoring the pressing need for innovative, cost-effective solutions.
This Research Topic aims to catalyze a paradigm shift in DMD treatment by spotlighting experimental, translational, and clinical studies poised to revolutionize current therapeutic approaches. By leveraging recent advances in molecular biology, regenerative medicine, and personalized healthcare, we aspire to not only enhance patient outcomes but also alleviate the economic strain on healthcare systems.
Furthermore, we encourage submissions that explore novel avenues such as gene therapy, stem cell research, and CRISPR-based interventions, offering hope for targeted, long-term solutions. Through collaborative efforts and interdisciplinary insights, we aim to accelerate the translation of scientific discoveries into tangible benefits for individuals affected by DMD and their families.
This Research Topic mainly highlights the critical role of changes in the dystrophin-glycoprotein complex and muscle fiber necrosis and regeneration. Contributors are encouraged to explore various aspects of DMD pathophysiology, such as molecular and cellular pathways, morphological tissue properties, clinical findings, novel biomarkers for disease monitoring and potential therapeutic approaches for patients. We welcome submissions of original research articles, systematic reviews, and case reports that offer insights into DMD pathophysiology and innovative therapeutic strategies.
Topic Editors declare no conflict of interest.
Considering this critical issue, the overarching goal of this Research Topic was to collect innovative proposals, aimed at deepening our comprehension of the mechanisms underlying muscle degeneration and regeneration in DMD. Beyond advancing scientific understanding, our overarching objective is to foster collaboration among researchers, catalyzing the exchange of insights and expertise in the pursuit of accelerated, science-driven innovation in this field.
Advances in science and rehabilitation techniques provide support only for secondary problems, such as muscle weakness and respiratory failure, seeking to improve the quality of life and prolong the survival of these patients, the fundamental challenge of curing DMD persists.
Several studies underscore the significant direct and indirect costs associated with treatment, with expenses escalating as the disease progresses.
Planning for patients' healthcare must factor in the expenses for the health system, underscoring the pressing need for innovative, cost-effective solutions.
This Research Topic aims to catalyze a paradigm shift in DMD treatment by spotlighting experimental, translational, and clinical studies poised to revolutionize current therapeutic approaches. By leveraging recent advances in molecular biology, regenerative medicine, and personalized healthcare, we aspire to not only enhance patient outcomes but also alleviate the economic strain on healthcare systems.
Furthermore, we encourage submissions that explore novel avenues such as gene therapy, stem cell research, and CRISPR-based interventions, offering hope for targeted, long-term solutions. Through collaborative efforts and interdisciplinary insights, we aim to accelerate the translation of scientific discoveries into tangible benefits for individuals affected by DMD and their families.
This Research Topic mainly highlights the critical role of changes in the dystrophin-glycoprotein complex and muscle fiber necrosis and regeneration. Contributors are encouraged to explore various aspects of DMD pathophysiology, such as molecular and cellular pathways, morphological tissue properties, clinical findings, novel biomarkers for disease monitoring and potential therapeutic approaches for patients. We welcome submissions of original research articles, systematic reviews, and case reports that offer insights into DMD pathophysiology and innovative therapeutic strategies.
Topic Editors declare no conflict of interest.
Keywords: Muscular Dystrophies, Muscle regeneration, muscular therapies, Cell-based therapies, Disease mechanisms
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
