About this Research Topic
Bacteria-host interactions represent a critical area of research, particularly in the context of infection and carcinogenesis. Microorganisms such as viruses and bacteria have long been implicated in the development of cancers, with notable examples including human papillomavirus (HPV) in cervical cancer and Helicobacter pylori in gastric cancer. Recent studies have expanded this understanding to include a broader range of bacteria, both pathogenic and commensal, in the carcinogenic process. This has sparked significant interest in the role of bacteria in the onset and progression of various neoplasms. While much of the research has concentrated on gastrointestinal cancers, where dysbiosis and bacterial infections are suspected contributors, emerging evidence suggests that bacteria also colonize tumor tissues in organs such as the breast, prostate, and lung. Despite these findings, the precise mechanisms by which bacteria influence tumor biology remain poorly understood, highlighting the need for further investigation.
This research topic aims to describe the complex interactions between bacteria and host tissues that contribute to carcinogenesis. Specifically, it seeks to identify and characterize pathogenic bacteria associated with cancer, understand the role of bacterial toxins in carcinogenic activity, and explore the impact of dysbiosis in gastrointestinal neoplasms. Additionally, the research will investigate bacterial colonization in various tumor tissues and the resulting immunological alterations due to bacteria-tumor interactions. By addressing these questions, the research aims to fill critical gaps in our understanding and potentially uncover new avenues for cancer prevention and treatment.
To gather further insights into the intricate dynamics of bacteria-host interactions in carcinogenesis, we welcome articles addressing, but not limited to, the following themes:
- Pathogenic bacteria associated with carcinogenesis
- Bacterial toxins with carcinogenic activity
- Dysbiosis in neoplasms of the gastrointestinal tract
- Bacterial colonization in tumor tissue
- Immunological alterations due to bacteria-tumor tissue interaction
This research topic aims to describe the complex interactions between bacteria and host tissues that contribute to carcinogenesis. Specifically, it seeks to identify and characterize pathogenic bacteria associated with cancer, understand the role of bacterial toxins in carcinogenic activity, and explore the impact of dysbiosis in gastrointestinal neoplasms. Additionally, the research will investigate bacterial colonization in various tumor tissues and the resulting immunological alterations due to bacteria-tumor interactions. By addressing these questions, the research aims to fill critical gaps in our understanding and potentially uncover new avenues for cancer prevention and treatment.
To gather further insights into the intricate dynamics of bacteria-host interactions in carcinogenesis, we welcome articles addressing, but not limited to, the following themes:
- Pathogenic bacteria associated with carcinogenesis
- Bacterial toxins with carcinogenic activity
- Dysbiosis in neoplasms of the gastrointestinal tract
- Bacterial colonization in tumor tissue
- Immunological alterations due to bacteria-tumor tissue interaction
Keywords: Bacteria, host, infection, carcinogenesis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
