About this Research Topic
Tumors of the middle ear and temporal bone are uncommon, and determining their primary site is often challenging. Due to their proximity to the skull base, nasopharynx, and paranasal sinuses, the differential diagnosis is broad, and obtaining a representative biopsy can be difficult. The recent update to the WHO classification of Head and Neck tumors emphasizes the scarcity of large studies related to the biology and treatment of these tumors. Surgery followed by gamma knife radiosurgery is the primary treatment for tumors originating from the middle and inner ear.
The aim of this Research Topic is to provide a comprehensive update on the current advancements in the pathogenesis and treatment of the rare tumors of the middle ear and temporal bone including paragangliomas, middle ear neuroendocrine tumors, endolymphatic sac tumors, middle ear squamous cell carcinoma and the vestibular schwannoma.
Systematic reviews on the biology and treatment strategies, Meta-analysis of treatment outcomes, and randomized clinical trials on new treatment approaches to of the tumors of the middle and inner ear according to the 5th edition of WHO classification of Head and Neck tumors are encouraged. New diagnostic methods and algorithms, and studies evaluating risk factors for the abovementioned neoplasms are encouraged.
The aim of this Research Topic is to provide a comprehensive update on the current advancements in the pathogenesis and treatment of the rare tumors of the middle ear and temporal bone including paragangliomas, middle ear neuroendocrine tumors, endolymphatic sac tumors, middle ear squamous cell carcinoma and the vestibular schwannoma.
Systematic reviews on the biology and treatment strategies, Meta-analysis of treatment outcomes, and randomized clinical trials on new treatment approaches to of the tumors of the middle and inner ear according to the 5th edition of WHO classification of Head and Neck tumors are encouraged. New diagnostic methods and algorithms, and studies evaluating risk factors for the abovementioned neoplasms are encouraged.
Keywords: molecular biology, treatment, tumors, middle and inner ear, paraganglioma, acoustic neuroma, inner ear tumor, middle ear tumor, pathogenesis, middle ear neuroendocrine tumor
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